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  • Jonsson, Maria, et al. (author)
  • Subcutaneous implanted chambers in different mouse strains as an animal model to study genetic stability during infection with Lyme disease Borrelia
  • 1995
  • In: Microbial Pathogenesis. - : Academic Press. - 0882-4010 .- 1096-1208. ; 18:2, s. 109-14
  • Journal article (peer-reviewed)abstract
    • Tissue metal net cages were implanted subcutaneously in BALB/cJ and C3H/Tif mice as an experimental model of Borrelia burgdorferi infection. B. burgdorferi sensu stricto strain Sh2-82 could be isolated up to 14 weeks after the inoculation. However, a significant difference in infectivity between the two mice strains was observed. C3H/Tif mice were more susceptible to developing chronic B. burgdorferi s.s. infections than BALB/cJ mice. Although a B. burgdorferi infection was established, no rearrangements in the ospA and ospB genes were observed in any of the infected mice.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Bergström, Sven (1)
Jonsson, Maria (1)
Elmros, Teodor (1)
University
Umeå University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year

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