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  • Rosengren, Annika M., et al. (author)
  • In situ detection of warfarin using time-correlated single-photon counting
  • 2011
  • In: Biochemical and Biophysical Research Communications - BBRC. - : Elsevier BV. - 0006-291X .- 1090-2104. ; 407:1, s. 60-62
  • Journal article (peer-reviewed)abstract
    • Here we report on a novel method for the direct in situ measurement of specific isomeric forms of the anticoagulant warfarin using time correlated single-photon counting (TCSPC) spectroscopy in conjunction with synthetic Sudlow I binding site receptors. The method is highly robust over the clinically significant concentration range, and demonstrates the potential of the binding site mimics in conjunction with the spectroscopic strategy employed here for the determination of this important pharmaceutical in clinical or even environmental samples.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Nicholls, Ian A. (1)
Andersson, Per Ola (1)
Karlsson, Björn C. G ... (1)
Rosengren, Annika M. (1)
Näslund, Inga (1)
University
Uppsala University (1)
Linnaeus University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2011 (1)

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