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  • Almgren, Birgitta, et al. (author)
  • Side effects of endotracheal suction in pressure and volume controlled ventilation
  • 2004
  • In: Chest. - : Elsevier BV. - 0012-3692 .- 1931-3543. ; 125:3, s. 1077-1080
  • Journal article (peer-reviewed)abstract
    • STUDY OBJECTIVES:To investigate the effects of endotracheal suction in volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) with an open suction system (OSS) or a closed suction system (CSS).DESIGN:Randomized comparison.SETTING:Animal research laboratory.PATIENTS:Twelve healthy anesthetized pigs.INTERVENTIONS:The effects of endotracheal suction during VCV and PCV with tidal volume (VT) of 14 mL/kg were compared. A 60-mm inner-diameter endotracheal tube was used. Ten-second suction was performed using OSS and CSS with 12F and 14F catheters connected to - 14 kPa vacuum.MEASUREMENTS AND RESULTS:Thirty minutes after suction in PCV, VT was still decreased by 27% (p < 0.001), compliance (Crs) by 28% (p < 0.001), and PaO(2) by 26% (p < 0.001); PaCO(2) was increased by 42% (p < 0.0001) and venous admixture by 158% (p = 0.003). Suction in VCV affected only Crs (decreased by 23%, p < 0.001) and plateau pressure (increased by 24%, p < 0.001). The initial impairment of gas exchange following suction in VCV was no longer statistically significant after 30 min.CONCLUSIONS:In conclusion, endotracheal suction causes lung collapse leading to impaired gas exchange, an effect that is more severe and persistent in PCV than in VCV.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Högman, Marieann (1)
Almgren, Birgitta (1)
Wickerts, Carl-Johan (1)
Heinonen, Erkki (1)
University
Uppsala University (1)
Karolinska Institutet (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
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