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- Rohrschneider, Markus, et al.
(author)
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A Novel Grid-based Visualization Approach for Metabolic Networks with Advanced Focus&Context View
- 2009
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In: Graph Drawing. - Berlin Heidelberg New Work : Springer. - 9783642118043 ; , s. 268-279
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Book chapter (peer-reviewed)abstract
- The universe of biochemical reactions in metabolic pathwayscan be modeled as a complex network structure augmented with domain specific annotations. Based on the functional properties of the involved reactions, metabolic networks are often clustered into so-called pathways inferred from expert knowledge. To support the domain expert in the exploration and analysis process, we follow the well-known Table Lens metaphor with the possibility to select multiple foci.In this paper, we introduce a novel approach to generate an interactive layout of such a metabolic network taking its hierarchical structure into account and present methods for navigation and exploration that preserve the mental map. The layout places the network nodes on a fixed rectilinear grid and routes the edges orthogonally between the node positions. Our approach supports bundled edge routes heuristically minimizing a given cost function based on the number of bends, the number of edge crossings and the density of edges within a bundle.
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