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  • Djos, Anna, 1983, et al. (author)
  • Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2 gene.
  • 2013
  • In: BMC medical genetics. - : Springer Science and Business Media LLC. - 1471-2350. ; 14:1
  • Journal article (peer-reviewed)abstract
    • Chromosomal instability is a hallmark of human cancer caused by errors in mitotic control and chromosome segregation. STAG2 encodes a subunit of the cohesion complex that participates in mitotic chromatid separation and was recently found to show low expression and inactivating mutations in Ewing's sarcoma, melanoma and glioblastoma.In the childhood tumor neuroblastoma (NB) segmental chromosomal alterations are associated with poor prognosis whereas tumors displaying whole chromosome gains and losses have a much better prognosis.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Kogner, Per (1)
Martinsson, Tommy, 1 ... (1)
Fransson, Susanne, 1 ... (1)
Djos, Anna, 1983 (1)
University
University of Gothenburg (1)
Karolinska Institutet (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2013 (1)

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