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  • Thuring, Camilla, et al. (author)
  • HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma
  • 2015
  • In: British Journal of Cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 113:6, s. 952-962
  • Journal article (peer-reviewed)abstract
    • Tumour cells can evade the immune system by dysregulation of human leukocyte antigens (HLA-I). Low quantity and/or altered quality of HLA-I cell surface expression is the result of either HLA-I alterations or dysregulations of proteins of the antigen-processing machinery (APM). Tapasin is an APM protein dedicated to the maturation of HLA-I and dysregulation of tapasin has been linked to higher malignancy in several different tumours.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Freyhult, Eva (1)
Junghans, Victoria (1)
Thuring, Camilla (1)
Paulsson, Kajsa M (1)
Follin, Elna (1)
Geironson Ulfsson, L ... (1)
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Harndahl, Mikkel (1)
Buus, Søren (1)
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University
Uppsala University (1)
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2015 (1)

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