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  • Koning, Nicolas R., et al. (author)
  • A C-H Activation Approach to the Tricyclic Core of Glionitrin A and B
  • 2022
  • In: ACS Omega. - : American Chemical Society (ACS). - 2470-1343. ; 7:14, s. 12329-12341
  • Journal article (peer-reviewed)abstract
    • Synthesis of diketopiperazines has been of long-standing interest in both natural product synthesis and medicinal chemistry. Here, we present an operationally convenient and efficient approach to the fused indoline-diketopiperazine tricyclic core of glionitrin A/B and related structures using a Pd-catalyzed C-H activation reaction to form the indoline five-membered ring. Exploratory work aimed at elaborating the tricyclic structures into the corresponding natural products is discussed.
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  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Strand, Daniel (1)
Koning, Nicolas R. (1)
University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2022 (1)

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