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  • Matuszewski, Damian J., et al. (author)
  • Comparison of Flow Cytometry and Image-Based Screening for Cell Cycle Analysis
  • 2016
  • In: Image Analysis And Recognition (ICIAR 2016). - Cham : Springer. ; , s. 623-630
  • Conference paper (peer-reviewed)abstract
    • Quantitative cell state measurements can provide a wealth of information about mechanism of action of chemical compounds and gene functionality. Here we present a comparison of cell cycle disruption measurements from commonly used flow cytometry (generating onedimensional signal data) and bioimaging (producing two-dimensional image data). Our results show high correlation between the two approaches indicating that image-based screening can be used as an alternative to flow cytometry. Furthermore, we discuss the benefits of image informatics over conventional single-signal flow cytometry.
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Type of publication
conference paper (1)
Type of content
peer-reviewed (1)
Author/Editor
Sintorn, Ida-Maria (1)
Wählby, Carolina (1)
Matuszewski, Damian ... (1)
Puigvert, Jordi Carr ... (1)
University
Uppsala University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2016 (1)

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