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  • Hermansen, Russell A, et al. (author)
  • Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeast.
  • 2015
  • In: BMC Evolutionary Biology. - : Springer Science and Business Media LLC. - 1471-2148. ; 15
  • Journal article (peer-reviewed)abstract
    • Selection on proteins is typically measured with the assumption that each protein acts independently. However, selection more likely acts at higher levels of biological organization, requiring an integrative view of protein function. Here, we built a kinetic model for de novo pyrimidine biosynthesis in the yeast Saccharomyces cerevisiae to relate pathway function to selective pressures on individual protein-encoding genes.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Liberles, David A. (1)
Knecht, Wolfgang (1)
Hermansen, Russell A (1)
Mannakee, Brian K (1)
Gutenkunst, Ryan N (1)
University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2015 (1)

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