| 91. |
- Heimbrand, Yvette, et al.
(author)
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Faktablad från Integrerad kustfiskövervakning 2022:4 Torhamn, södra Egentliga Östersjön, 2002–2021
- 2022
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Reports (other academic/artistic)abstract
- Den integrerade kustfiskövervakningen i Torhamn visade en tendens till minskning av abborre och ökning av karpfiskar i provfiskefångsten. Abborrens tillväxt har ökat sedan 2002, men indikatorn L90 som representerar storleken på stora abborrar har inte förändrats över tid. Den främmande arten svartmunnad smörbult har påträffats i låga tätheter i provfisket sedan 2015. Sill har ökat i förekomst, medan sarv, id och gädda har minskat. Hälsotillståndet hos abborre i Torhamn har blivit sämre. Inverkan på abborrens hälsotillstånd talar för att fisken är exponerad för något eller några kemiska ämnen. Liknande förändringar har även bserverats i de andra referensområdena för kustfisk, och kan tyda på att det är fråga om en likartad och generell inverkan på fiskens hälsa längs våra kuster. Att abborre växer snabbare är sannolikt en effekt av den ökade vattentemperaturen, dock är abborrarna unga och som äldst 3 år i fångsten 2021. Det är oroande att gädda som är en nyckelart i ekosystemet minskar och att abborrens hälsotillstånd har försämrats i ett referensområde som anses vara relativt opåverkat av direkt mänsklig aktivitet. Det är därför angeläget att klarlägga om det är okända miljögifter eller kända miljögifter som inte övervakas idag, eller andra miljöfaktorer som orsakar den försämrade hälsan hos abborren.
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| 92. |
- Holmberg, Anna, 1974, et al.
(author)
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Does waterborne citalopram affect the aggressive and sexual behaviour of rainbow trout and guppy?
- 2011
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In: Journal of hazardous materials. - : Elsevier BV. - 1873-3336 .- 0304-3894. ; 187:1-3, s. 596-9
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Journal article (peer-reviewed)abstract
- Citalopram is one of several selective serotonin reuptake inhibitors (SSRIs) commonly found in treated sewage effluents. Accordingly, there are concerns about possible adverse effects of SSRIs on aquatic organisms, particularly behavioural effects similar to those associated with SSRI use in humans. Rainbow trout fry and adult male guppies were therefore exposed to waterborne citalopram, ranging from environmentally relevant to high concentrations (1, 10, 100 μg/L) for 3-7 days. Under these experimental conditions citalopram does not appear to cause significant effects on aggression in rainbow trout fry or on sexual behaviour in male guppies. This may be explained by a relatively low uptake of citalopram from water to fish.
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| 93. |
- Kling, Peter, 1968, et al.
(author)
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Gender-specific proteomic responses in zebrafish liver following exposure to a selected mixture of brominated flame retardants
- 2008
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In: Ecotoxicology and Environmental Safety. - : Elsevier Inc. - 1090-2414 .- 0147-6513. ; 71:2, s. 319-27
-
Journal article (peer-reviewed)abstract
- Proteomic effect screening in zebrafish liver was performed to generate hypotheses following exposure (21 days) to a structurally diverse mixture of brominated flame retardants (BFRs). Fish were exposed to two doses (10 and 100 nmol/g feed). Two-dimensional gel-electrophoresis, image analysis and MALDI-TOF mass-spectrometry revealed 13 and 19 significant responses in males and females, respectively. Effects on proteins related to cellular maintenance and stress were observed in both genders. Regulated proteins were gender-specific, but functionally indicated common protective responses (peroxiredoxin 6 and Zgc:92891 in males and transketolase in females) suggesting oxidative stress. Betaine homocysteine methyltransferase (BHMT) was induced in both genders. In addition a female-specific downregulation of ironhomeostatic proteins (iron-regulatory protein 1 and transferrin) were observed. Our proteomic approach revealed novel responses that suggest important gender-specific sensitivity to BFRs that should be considered when interpreting adverse effects of BFRs.
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| 94. |
- Kling, Peter, 1968, et al.
(author)
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Proteomic studies in zebrafish liver cells exposed to the brominated flame retardants HBCD and TBBPA.
- 2009
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In: Ecotoxicology and environmental safety. - : Elsevier BV. - 1090-2414 .- 0147-6513. ; 72:7, s. 1985-93
-
Journal article (peer-reviewed)abstract
- Proteomic effect screening in zebrafish liver cells was performed to generate hypotheses regarding single and mixed exposure to the BFRs HBCD and TBBPA. Responses at sublethal exposure were analysed by two-dimensional gel electrophoresis followed by MALDI-TOF and FT-ICR protein identification. Mixing of HBCD and TBBPA at sublethal doses of individual substances seemed to increase toxicity. Proteomic analyses revealed distinct exposure-specific and overlapping responses suggesting novel mechanisms with regard to HBCD and TBBPA exposure. While distinct HBCD responses were related to decreased protein metabolism, TBBPA revealed effects related to protein folding and NADPH production. Overlapping responses suggest increased gluconeogenesis (GAPDH and aldolase) while distinct mixture effects suggest a pronounced NADPH production and changes in proteins related to cell cycle control (prohibitin and crk-like oncogene). We conclude that mixtures containing HBCD and TBBPA may result in unexpected effects highlighting proteomics as a sensitive tool for detecting and hypothesis generation of mixture effects.
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| 95. |
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| 96. |
- Kristiansson, Erik, 1978, et al.
(author)
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Characterization of the Zoarces viviparus liver transcriptome using massively parallel pyrosequencing
- 2009
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In: BMC Genomics. - : Springer Science and Business Media LLC. - 1471-2164. ; 10:345
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Journal article (peer-reviewed)abstract
- Background The teleost Zoarces viviparus (eelpout) lives along the coasts of Northern Europe and has long been an established model organism for marine ecology and environmental monitoring. The scarce information about this species genome has however restrained the use of efficient molecular-level assays, such as gene expression microarrays. Results In the present study we present the first comprehensive characterization of the Zoarces viviparus liver transcriptome. From 400,000 reads generated by massively parallel pyrosequencing, more than 50,000 pieces of putative transcripts were assembled, annotated and functionally classified. The data was estimated to cover roughly 40% of the total transcriptome and homologues for about half of the genes of Gasterosteus aculeatus (stickleback) were identified. The sequence data was consequently used to design an oligonucleotide microarray for large-scale gene expression analysis. Conclusion Our results show that one run using a Genome Sequencer FLX from 454 Life Science/Roche generates enough genomic information for adequate de novo assembly of a large number of genes in a higher vertebrate. The generated sequence data, including the validated microarray probes, are publicly available to promote genome-wide research in Zoarces viviparus.
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| 97. |
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| 98. |
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| 99. |
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