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Search: WFRF:(Ögren Mats)

  • Result 11-20 of 28
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  • Eliasson, Åsa, et al. (author)
  • Incidence and risk of venous thromboembolism in patients with verified arterial thrombosis : a population study based on 23,796 consecutive autopsies
  • 2006
  • In: Journal of Thrombosis and Haemostasis. - : Elsevier BV. - 1538-7933 .- 1538-7836. ; 4:9, s. 1897-1902
  • Journal article (peer-reviewed)abstract
    • Background: The relationship between atherothrombotic disease and venous thromboembolism (VTE) remains unclear. Patients and methods: In a cohort of 23 796 consecutive autopsies, performed using a standardized procedure and representing 84% of all in-hospital deaths between 1970 and 1982 in an urban Swedish population, we investigated the relationship between verified arterial thrombosis and VTE, with the hypothesis that patients with thrombosis in major artery segments have increased odds of VTE. Results: We found an increased risk of VTE in patients with arterial thrombosis (Odds ratio; OR adjusted for gender and age 1.4, 95% confidence interval; CI 1.3-1.5) (P < 0.001). Patients with cervico-cranial and peripheral artery thrombosis had an excess risk even when controlling for age and major concomitant diseases. A negative association between coronary thrombosis and VTE in the univariate analysis (OR 0.7; 95% CI 0.6-0.8) (P < 0.001), was less pronounced in the multivariate analysis (OR 0.8; 95% CI 0.7-1.0) (P = 0.016). Conclusions: A positive association between atherothrombosis and VTE was confirmed, except in patients with coronary thrombosis, where IHD as competing death cause is a possible confounder. Our findings indicate a potential for directed prevention, but may also imply similarities in etiology.
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  • Fowkes, F. G. R., et al. (author)
  • Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events
  • 2014
  • In: European Journal of Preventive Cardiology. - : Oxford University Press (OUP). - 2047-4881 .- 2047-4873. ; 21:3, s. 310-320
  • Journal article (peer-reviewed)abstract
    • Background The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events. Methods Subjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS + ABI, were fitted for the primary outcome of major coronary events. Results In predicting events in the external validation dataset, C-index for the FRS was 0.672 (95% CI 0.599 to 0.737) in men and 0.578 (95% CI 0.492 to 0.661) in women. The FRS + ABI led to a small increase in C-index in men to 0.685 (95% CI 0.612 to 0.749) and large increase in women to 0.690 (95% CI 0.605 to 0.764) with net reclassification improvement (NRI) of 4.3% (95% CI 0.0 to 7.6%, p = 0.050) and 9.6% (95% CI 6.1 to 16.4%, p < 0.001), respectively. Restricting the FRS + ABI model to those with FRS intermediate 10-year risk of 10 to 19% resulted in higher NRI of 15.9% (95% CI 6.1 to 20.6%, p < 0.001) in men and 23.3% (95% CI 13.8 to 62.5%, p = 0.002) in women. However, incorporating ABI in an improved newly fitted risk factor model had a nonsignificant effect: NRI 2.0% (95% CI 2.3 to 4.2%, p = 0.567) in men and 1.1% (95% CI 1.9 to 4.0%, p = 0.483) in women. Conclusions An ABI risk model may improve prediction especially in individuals at intermediate risk and when performance of the base risk factor model is modest.
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  • Result 11-20 of 28
Type of publication
journal article (21)
book chapter (4)
doctoral thesis (2)
conference paper (1)
Type of content
peer-reviewed (22)
other academic/artistic (4)
pop. science, debate, etc. (2)
Author/Editor
Ögren, Mats (20)
Bergqvist, David (10)
Björck, Martin (9)
Acosta, Stefan (9)
Sternby, Nils-Herman (4)
Hedblad, Bo (4)
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Lindblad, Bengt (3)
Janzon, Lars (3)
Engström, Gunnar (2)
Sternby, Nils (2)
Bengtsson, Henrik (2)
Ögren, Anders (2)
Ögren, Mikael (1)
Lundqvist, Hans (1)
Verbaan, Hans (1)
Ekberg, Olle (1)
Alhadad, Alaa (1)
Zdanowski, Zbigniew (1)
Acosta, Stefan, 1967 ... (1)
Lindblad, Bengt, Doc ... (1)
Koenig, W. (1)
Agenäs, Sigrid (1)
Hofman, A (1)
Cederwall, Martin, 1 ... (1)
Clough, Yann (1)
Garmo, Hans (1)
Norlén, Olov (1)
Sjögren, Leif (1)
Ahlberg, Mats (1)
Aronsson, Niklas (1)
Bennett, David (1)
Gardfjell, Maria (1)
Gunnarsson, Carina (1)
Olausson, Inger (1)
Printz Emond, Maria (1)
Ögren, Elisabeth (1)
Artursson, Per (1)
Lazorova, Lucia (1)
Jansson, Jonas (1)
Bolling, Anne (1)
Långström, Bengt (1)
Hellman, Per (1)
Price, J. F. (1)
Palmqvist, Göran (1)
Hjort, Mattias, 1972 ... (1)
Nordberg, Agneta (1)
Stehouwer, C D A (1)
Brink, Lars, 1943 (1)
Sehammar, Håkan (1)
Larsson, Mats, Profe ... (1)
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University
Uppsala University (21)
Lund University (16)
Chalmers University of Technology (1)
Karolinska Institutet (1)
VTI - The Swedish National Road and Transport Research Institute (1)
Language
English (23)
Swedish (5)
Research subject (UKÄ/SCB)
Medical and Health Sciences (13)
Social Sciences (3)
Natural sciences (2)
Humanities (2)
Engineering and Technology (1)

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