| 11. |
- Ivanov, Sergey A., et al.
(author)
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Temperature evolution of structural and magnetic properties of stoichiometric LiCu2O2 : Correlation of thermal expansion coefficient and magnetic order
- 2014
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In: Solid State Sciences. - : Elsevier BV. - 1293-2558 .- 1873-3085. ; 34, s. 97-101
-
Journal article (peer-reviewed)abstract
- Temperature-dependent crystallographic and magnetic studies on stoichiometric single crystals of LiCu2O2 are reported. The temperature dependence of the lattice parameters was extracted from X-ray powder diffractograms collected on crushed single crystals, from 12 K to 295 K. The magnetic properties are similar to earlier findings demonstrating antiferromagnetic ordering below 25 K. Evidence of magnetoelastic coupling is observed in the thermal expansion along the c-direction; not only at the low temperature antiferromagnetic transitions, but an anomalous behavior of the thermal expansion indicate magnetoelastic coupling also to the magnetic ordering related to a weak spontaneous magnetic moment appearing at 150 K. Ac-susceptibility measurements at different frequencies and superposed dc-fields are employed to further characterize this magnetic anomaly.
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| 12. |
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| 13. |
- Kotecha, S, et al.
(author)
-
Congenital diaphragmatic hernia
- 2012
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In: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 39:4, s. 820-829
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Journal article (peer-reviewed)
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| 14. |
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| 15. |
- Lødrup Carlsen, K C, et al.
(author)
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Assessment of problematic severe asthma in children.
- 2011
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In: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 37:2, s. 432-40
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Journal article (peer-reviewed)abstract
- Assessment of problematic severe asthma in children should be performed in a step-wise manner to ensure an optimal approach. A four-step assessment scheme is proposed. First, a full diagnostic work-up is performed to exclude other diseases which mimic asthma. Secondly, a multi-disciplinary assessment is performed to identify issues that may need attention, including comorbidities. Thirdly, the pattern of inflammation is assessed, and finally steroid responsiveness is documented. Based upon these four steps an optimal individualised treatment plan is developed. In this article the many gaps in our current knowledge in all these steps are highlighted, and recommendations for current clinical practice and future research are made. The lack of good data and the heterogeneity of problematic severe asthma still limit our ability to optimise the management on an individual basis in this small, but challenging group of patients.
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| 16. |
- Brand, Paul L P, et al.
(author)
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Classification and pharmacological treatment of preschool wheezing: changes since 2008.
- 2014
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In: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 43:4, s. 1172-1177
-
Journal article (peer-reviewed)abstract
- Since the publication of the European Respiratory Society Task Force report in 2008, significant new evidence has become available on the classification and management of preschool wheezing disorders. In this report, an international consensus group reviews this new evidence and proposes some modifications to the recommendations made in 2008. Specifically, the consensus group acknowledges that wheeze patterns in young children vary over time and with treatment, rendering the distinction between episodic viral wheeze and multiple-trigger wheeze unclear in many patients. Inhaled corticosteroids remain first-line treatment for multiple-trigger wheeze, but may also be considered in patients with episodic viral wheeze with frequent or severe episodes, or when the clinician suspects that interval symptoms are being under reported. Any controller therapy should be viewed as a treatment trial, with scheduled close follow-up to monitor treatment effect. The group recommends discontinuing treatment if there is no benefit and taking favourable natural history into account when making decisions about long-term therapy. Oral corticosteroids are not indicated in mild-to-moderate acute wheeze episodes and should be reserved for severe exacerbations in hospitalised patients. Future research should focus on better clinical and genetic markers, as well as biomarkers, of disease severity.
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| 17. |
- Carlsen, KH, et al.
(author)
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Childhood asthma in the Year of the Lung
- 2010
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In: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 36:1, s. 6-7
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Journal article (other academic/artistic)
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| 18. |
- Chung, KF, et al.
(author)
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International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
- 2014
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In: The European respiratory journal. - : European Respiratory Society (ERS). - 1399-3003 .- 0903-1936. ; 43:2, s. 343-373
-
Journal article (peer-reviewed)abstract
- Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American Thoracic Society, reviewed the definition and provided recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults.A literature review was performed, followed by discussion by an expert committee according to the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach for development of specific clinical recommendations.When the diagnosis of asthma is confirmed and comorbidities addressed, severe asthma is defined as asthma that requires treatment with high dose inhaled corticosteroids plus a second controller and/or systemic corticosteroids to prevent it from becoming “uncontrolled” or that remains “uncontrolled” despite this therapy. Severe asthma is a heterogeneous condition consisting of phenotypes such as eosinophilic asthma. Specific recommendations on the use of sputum eosinophil count and exhaled nitric oxide to guide therapy, as well as treatment with anti-IgE antibody, methotrexate, macrolide antibiotics, antifungal agents and bronchial thermoplasty are provided.Coordinated research efforts for improved phenotyping will provide safe and effective biomarker-driven approaches to severe asthma therapy.
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| 19. |
- Chunilall, V., et al.
(author)
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A CP/MAS 13C-NMR study of cellulose fibril aggregation in eucalyptus dissolving pulps during drying and the correlation between aggregate dimensions and chemical reactivity
- 2010
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In: Holzforschung. - 0018-3830 .- 1437-434X. ; 64:6, s. 693-698
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Journal article (peer-reviewed)abstract
- Changes in supramolecular properties of cellulose I, namely its lateral fibril aggregate dimension (LFAD), in bleached hardwood acid bisulphite pulp during drying was studied using cross-polarization/magic angle spinning carbon-13 nuclear magnetic resonance (CP/MAS 13C-NMR) in combination with spectral fitting. A significant change in aggregate dimensions was noticed when each of the pulp grades were oven dried. The effect of drying was further investigated with pulp samples subjected to different drying methods. A comparison of a harsh oven drying, mild and rapid air drying, and a very mild and slow condition drying showed that the LFAD of the material decreases in the following order: oven drying > air drying > condition drying. The correlation between the total extractable material S10 (%) and LFAD and also the LFAD increment (ΔLFAD in %) are presented and shown to be intimately related. This means that the method of drying influences the size of the fibril aggregate dimensions and depends on the presence of extractable material within the fibre cell wall. Reactivity studies were carried out based on the acetylation of cotton linters and commercial 96α pulp. Results indicate that the initial reaction rate is proportional to the specific surface area of the two cellulose pulp samples. Accordingly, the specific surface area is directly related to initial reactivity of the performed acetylation. We demonstrated that it is possible to control the LFAD and hence specific surface area in laboratory-produced pulps 91α, 92α, and 96α by the drying method. Thus controlling LFAD can probably be one viable route for controlling the initial reactivity of dissolving pulp towards acetylation.
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| 20. |
- Hedlin, G, et al.
(author)
-
An update on paediatric asthma
- 2012
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In: European respiratory review : an official journal of the European Respiratory Society. - : European Respiratory Society (ERS). - 1600-0617. ; 21:125, s. 175-85
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Journal article (peer-reviewed)
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