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Träfflista för sökning "WFRF:(Ingre M) "

Search: WFRF:(Ingre M)

  • Result 11-20 of 67
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  • Lee, Teresa, et al. (author)
  • Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients
  • 2011
  • In: Human Molecular Genetics. - : Oxford University Press (OUP). - 0964-6906 .- 1460-2083. ; 20:9, s. 1697-1700
  • Journal article (peer-reviewed)abstract
    • Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disease primarily affecting motor neurons. We recently identified intermediate-length polyglutamine (polyQ) expansions (27-33 Qs) in ataxin 2 as a genetic risk factor for sporadic ALS in North American ALS patients. To extend these findings, we assessed the ataxin 2 polyQ repeat length in 1294 European ALS patients and 679 matched healthy controls. We observed a significant association between polyQ expansions and ALS (>30 Qs; P= 6.2 × 10(-3)). Thus, intermediate-length ataxin 2 polyQ repeat expansions are associated with increased risk for ALS also in the European cohort. The specific polyQ length cutoff, however, appears to vary between different populations, with longer repeat lengths showing a clear association. Our findings support the hypothesis that ataxin 2 plays an important role in predisposing to ALS and that polyQ expansions in ataxin 2 are a significant risk factor for the disease.
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  • van Eijk, RPA, et al. (author)
  • TRICALS: creating a highway toward a cure
  • 2020
  • In: Amyotrophic lateral sclerosis & frontotemporal degeneration. - : Informa UK Limited. - 2167-9223 .- 2167-8421. ; 21:7-8, s. 496-501
  • Journal article (peer-reviewed)
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  • Al-Chalabi, Ammar, et al. (author)
  • July 2017 ENCALS statement on edaravone
  • 2017
  • In: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. - : TAYLOR & FRANCIS LTD. - 2167-8421 .- 2167-9223. ; 18:7-8, s. 471-474
  • Journal article (peer-reviewed)abstract
    • n/a
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  • Result 11-20 of 67
Type of publication
journal article (45)
conference paper (19)
reports (1)
other publication (1)
doctoral thesis (1)
Type of content
peer-reviewed (43)
other academic/artistic (24)
Author/Editor
Ingre, M (29)
Akerstedt, T (19)
Kecklund, G (15)
Axelsson, J (11)
Andersen, Peter M. (9)
Ingre, Caroline (9)
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Lekander, M (6)
Fang, F (6)
Kecklund, Göran (5)
Birve, Anna (5)
Van Damme, P (4)
de Carvalho, Mamede (4)
Åkerstedt, Torbjörn (4)
Ingre, Michael (4)
Al-Chalabi, A (4)
van Leeuwen, Wessel ... (3)
Corcia, Philippe (3)
Andersen, Peter M., ... (3)
Weber, Markus (3)
Press, R (3)
Meyer, Thomas (3)
Sorjonen, K (3)
Kumar, A. (2)
Evans, M. (2)
Carrero, JJ (2)
Stephens, G. (2)
Al-Chalabi, Ammar (2)
Heverin, M (2)
van Damme, Philip (2)
Couratier, Philippe (2)
Hardiman, Orla (2)
van den Berg, Leonar ... (2)
Soderstrom, M (2)
Olsson, B (2)
Peters, B (2)
Anund, A (2)
Nilsonne, G (2)
Murray, D. (2)
Camu, William (2)
Gitler, Aaron D. (2)
Chio, Adriano (2)
Danielsson, Olof (2)
Desnuelle, Claude (2)
Grehl, Torsten (2)
Grosskreutz, Julian (2)
Koritnik, Blaz (2)
Ludolph, Albert (2)
Petri, Susanne (2)
Salachas, Francois (2)
Svenstrup, Kirsten (2)
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University
Karolinska Institutet (61)
Umeå University (14)
Stockholm University (5)
Linköping University (3)
Uppsala University (1)
Lund University (1)
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Linnaeus University (1)
VTI - The Swedish National Road and Transport Research Institute (1)
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Language
English (67)
Research subject (UKÄ/SCB)
Medical and Health Sciences (20)
Natural sciences (1)
Social Sciences (1)

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