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11.	Baehr, A, et al. (author) Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs 2020 In: Circulation. - 1524-4539. ; 142:9, s. 868-881 Journal article (peer-reviewed)
12.	Espaillat, Akbar, master, 1988-, et al. (author) Binding of non-canonical peptidoglycan controls Vibrio cholerae broad spectrum racemase activity 2021 In: Computational and Structural Biotechnology Journal. - : Elsevier. - 2001-0370. ; 19, s. 1119-1126 Journal article (peer-reviewed)abstract Broad-spectrum amino acid racemases (Bsrs) enable bacteria to generate non-canonical D-amino acids (NCDAAs), whose roles and impact on microbial physiology, including modulation of cell wall structure and dissolution of biofilms, are just beginning to be appreciated. Here we used a diverse array of structural, biochemical and molecular simulation studies to define and characterize how BsrV is post-translationally regulated. We discovered that contrary to Vibrio cholerae alanine racemase AlrV highly compacted active site, BsrV’s is broader and can be occupied by cell wall stem peptides. We found that peptidoglycan peptides modified with NCDAAs are better stabilized by BsrV’s catalytic cavity and show better inhibitory capacity than canonical muropeptides. Notably, BsrV binding and inhibition can be recapitulated by undigested peptidoglycan sacculi as it exists in the cell. Docking simulations of BsrV binding the peptidoglycan polymer generate a model where the peptide stems are perfectly accommodated and stabilized within each of the dimeŕs active sites. Taking these biochemical and structural data together, we propose that inhibition of BsrV by peptidoglycan peptides underlies a negative regulatory mechanism to avoid excessive NCDAA production. Our results collectively open the door to use “à la carte” synthetic peptides as a tool to modulate DAAs production of Bsr enzymes.
13.	Nilsson, S, et al. (author) Gold-coated fused-silica sheathless electrospray emitters based on vapor-deposited titanium adhesion layers 2003 In: Rapid communications in mass spectrometry. ; 17:14, s. 1535-1540 Journal article (peer-reviewed)
14.	Proceedings of the 17th International Conference on Computers in Education (ICCE) 2009 2009 Editorial proceedings (other academic/artistic)
15.	Thorslund, Sara, et al. (author) Essential components in an integrated platform for on-site screening of anabolic androgenic steroids in biological samples 2004 In: Micro Total Analysis Systems 2004. - 0854046437 Conference paper (peer-reviewed)abstract In this abstract new results concerning the introduction of a biological sample into a mu TAS, the avoidance of unspecific absorbance in the mu TAS and the interfacing to off-chip detection (e.g. Mass spectrometry, MS) for verification are presented.

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Result 11-15 of 15

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Type of publication: journal article (12); conference paper (2); editorial proceedings (1)

Type of content: peer-reviewed (13); other academic/artistic (2)

Author/Editor: KLETT, A (5); Klett, K (3); Seregard, S (2); Korsmo, H (2); Hassan, S (2); Cieslik, K. (2); show more...; Moreira, C (2); Bobrova, N. (2); Johansson, Tord (2); Eyrich, W. (2); Kilian, K (2); Fasina, O (2); Chiwanga, FS (2); Cassoux, N (2); Desjardins, L (2); Bornfeld, N (2); Sagoo, MS (2); Saakyan, S (2); Midena, E (2); Parrozzani, R (2); Kivela, TT (2); Ali, AM (2); All-Eriksson, C (2); Laugwitz, KL (2); Popovic, MB (2); Csoka, M. (2); Silva, S (2); Balwierz, W (2); Geyer, R. (2); Hinkel, R (2); Kupatt, C (2); Eisenstein, RA (2); Franz, J (2); Hertzog, DW (2); BERTOLOTTO, L (2); BUZZO, A (2); DEBEVEC, PT (2); DRIJARD, D (2); EASO, S (2); HUGHES, SA (2); KIRSEBOM, K (2); LOVETERE, M (2); Abdallah, E (2); Kruger, M (2); Davidson, A (2); Hessissen, L (2); Svojgr, K (2); Bowman, R (2); Fabian, ID (2); Abdullahi, SU (2); show less...

University: Karolinska Institutet (7); Uppsala University (4); University of Gothenburg (2); Umeå University (1); Royal Institute of Technology (1); Linnaeus University (1)

Language: English (14); Swedish (1)

Research subject (UKÄ/SCB): Natural sciences (6); Medical and Health Sciences (3); Engineering and Technology (1)

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