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Search: WFRF:(Rintala A)

  • Result 11-20 of 23
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  • Bonnechere, B, et al. (author)
  • Mobile health solutions: An opportunity for rehabilitation in low- and middle income countries?
  • 2023
  • In: Frontiers in public health. - : Frontiers Media SA. - 2296-2565. ; 10, s. 1072322-
  • Journal article (peer-reviewed)abstract
    • Mobile health (mHealth) development has advanced rapidly, indicating promise as an effective patient intervention. mHealth has many potential benefits that could help the treatment of patients, and the development of rehabilitation in low- and middle-income countries (LMICs). mHealth is a low-cost option that does not need rapid access to healthcare clinics or employees. It increases the feasibility and rationality of clinical treatment expectations in comparison to the conventional clinical model of management by promoting patient adherence to the treatment plan. mHealth can also serve as a basis for formulating treatment plans and partially compensate for the shortcomings of the traditional model. In addition, mHealth can help achieve universal rehabilitation service coverage by overcoming geographical barriers, thereby increasing the number of ways patients can benefit from the rehabilitation service, and by providing rehabilitation to individuals in remote areas and communities with insufficient healthcare services. However, despite these positive potential aspects, there is currently only a very limited number of studies performed in LMICs using mHealth. In this study, we first reviewed the current evidence supporting the use of mHealth in rehabilitation to identify the countries where studies have been carried out. Then, we identify the current limitations of the implementation of such mHealth solutions and propose a 10-point action plan, focusing on the macro (e.g., policymakers), meso (e.g., technology and healthcare institutions), and micro (e.g., patients and relatives) levels to ease the use, validation, and implementation in LMICs and thus participate in the development and recognition of public health and rehabilitation in these countries.
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  • Hotakainen, K, et al. (author)
  • Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer
  • 2006
  • In: International Journal of Oncology. - 1019-6439. ; 28:1, s. 95-101
  • Journal article (peer-reviewed)abstract
    • Tumor-associated trypsin inhibitor (TATI) is a marker of mucinous ovarian carcinoma, but it is also widely expressed in other malignant tumors and normal human tissues. Elevated serum concentrations of TATI are of prognostic value in ovarian, kidney, and bladder cancer. Tumor-associated trypsin is co-expressed with TATI in many malignancies and is thought to be involved in tumor invasion. TATI mRNA has been shown to be overexpressed in bladder cancer. We therefore studied whether trypsinogen expression also can be detected in bladder cancer and how this and TATI expression are associated with the clinicopathological characteristics of the tumors. We used RT-PCR, in situ hybridization and immunohistochemistry to detect trypsinogen-and TATI mRNA and protein in tissue samples from 28 bladder cancer patients and ten benign urothelia. TATI expression was detected in all benign tissues and non-invasive tumors. However, the expression was lower in the muscle-invasive tumors (pT2; n=5), whereas trypsinogen expression was seen in all but one non-invasive tumor. We conclude that trypsinogen is expressed in both malignant and benign bladder epithelium, whereas TATI expression decreases with increasing stage and grade of the tumor. This may suggest that a balanced expression of TATI and trypsinogen is required in normal tissue and that this balance is disrupted during tumor progression.
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  • Marklund, Björn, et al. (author)
  • Retention Footprint : Visualising and monitoring student retention in study programmes across Europe
  • 2012
  • In: Proceedings of the 40th SEFI Annual Conference 2012 - Engineering Education 2020. - : European Society for Engineering Education (SEFI). - 9782873520052
  • Conference paper (peer-reviewed)abstract
    • Most of the universities across Europe have their own way of measuring and monitoring student progression, retention, attrition, drop out, etc. The way of holding statistics and calculating indicators differs as well as the demands of different stakeholders within the universities and society. ATTRACT (Enhance the Attractiveness of Studies in Science and Technology) is a European Commission supported project aiming to increase knowledge and inform practice about student recruitment and retention in engineering and technology education. Within this project partners agreed to test and evaluate a method of visualising and monitoring student retention in a so-called footprint in selected fields of programmes. The tool was originally developed in the Swedish project "Ung Ingenjör" http://www.kth.se/unging The test had three sub aims: 1. The overall level was to test if the visualising method can be used to compare/benchmark engineering education in Europe concerning retention. 2. The next level was to test and evaluate how the method can be used in assessing engineering education. 3. The final level aimed to test if the method can be used to compare different student groups concerning study background coupled to retention. The footprint itself can only be an indicator as such and the reasons behind study progress, drop out, low graduation rate etc. can only be found through further quantitative and qualitative analysis and discussions. The results from this exercise show the complexity of finding reasons and proper actions. The results also show that the way of monitoring facts and figures in a visual presentation trigs the viewer to dig deeper and do further analysis.
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