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11.	Perry, JRB, et al. (author) Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche 2014 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 514:7520, s. 92- Journal article (peer-reviewed)
12.	Sabater-Lleal, M, et al. (author) Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease 2013 In: Circulation. - 1524-4539. ; 128:12, s. 1310-1324 Journal article (peer-reviewed)
13.	Randall, JC, et al. (author) Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits 2013 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 9:6, s. e1003500- Journal article (peer-reviewed)
14.	Ruth, KS, et al. (author) Genetic insights into biological mechanisms governing human ovarian ageing 2021 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 596:7872, s. 393-397 Journal article (peer-reviewed)
15.	Shungin, Dmitry, et al. (author) New genetic loci link adipose and insulin biology to body fat distribution. 2015 In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 518:7538, s. 187-378 Journal article (peer-reviewed)abstract Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms.
16.	Winkler, TW, et al. (author) Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2016 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 12:6, s. e1006166- Journal article (peer-reviewed)
17.	Winkler, TW, et al. (author) The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 2015 In: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404 .- 1553-7390. ; 11:10, s. e1005378- Journal article (peer-reviewed)
18.	de Moor, MHM, et al. (author) Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder 2015 In: JAMA psychiatry. - : American Medical Association (AMA). - 2168-6238 .- 2168-622X. ; 72:7, s. 642-650 Journal article (peer-reviewed)
19.	Frazier-Wood, Alexis C., et al. (author) Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses 2016 In: Nature Genetics. - : Nature Research (part of Springer Nature). - 1061-4036 .- 1546-1718. ; 48, s. 624- Journal article (peer-reviewed)abstract Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is genetically correlated with both of these traits, has not yet been studied with genome-wide data. We conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n = 161,460), and neuroticism (n = 170,911). We identify 3 variants associated with subjective well-being, 2 variants associated with depressive symptoms, and 11 variants associated with neuroticism, including 2 inversion polymorphisms. The two loci associated with depressive symptoms replicate in an independent depression sample. Joint analyses that exploit the high genetic correlations between the phenotypes (vertical bar(p) over cap vertical bar approximate to 0.8) strengthen the overall credibility of the findings and allow us to identify additional variants. Across our phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association.
20.	Okbay, A, et al. (author) Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses 2016 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 48:8, s. 970-970 Journal article (peer-reviewed)

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Result 11-20 of 52

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Type of publication: journal article (52)

Type of content: peer-reviewed (51); other academic/artistic (1)

Author/Editor: Schlessinger, D. (23); Boomsma, DI (20); Mangino, Massimo (19); Hottenga, JJ (18); Groop, Leif (18); Ferrucci, L (18); show more...; Wareham, Nicholas J. (18); Thorsteinsdottir, Un ... (18); Stefansson, Kari (18); Abecasis, Goncalo R. (18); Luan, Jian'an (18); Hayward, C. (18); Rudan, Igor (17); McCarthy, Mark I (17); van Duijn, Cornelia ... (17); Boehnke, Michael (17); Esko, T (17); Metspalu, A (17); Rudan, I. (17); Tanaka, T. (16); Salomaa, Veikko (16); Hofman, A (16); Montgomery, GW (16); Uitterlinden, AG (16); Martin, NG (16); Campbell, H (16); Gieger, Christian (16); Jarvelin, Marjo-Riit ... (16); Gieger, C (16); Wilson, James F. (16); Polašek, O. (16); Willemsen, G (15); van Duijn, CM (15); Campbell, Harry (15); Deloukas, Panos (15); Mohlke, Karen L (15); Wichmann, H. Erich (15); Samani, Nilesh J. (15); Amin, N (14); Teumer, A (14); Ohlsson, Claes, 1965 (14); Laakso, Markku (14); Tuomilehto, Jaakko (14); Thorleifsson, Gudmar (14); Barroso, Ines (14); Eriksson, JG (14); Wilson, JF (14); Thorsteinsdottir, U (14); Stefansson, K (14); Metspalu, Andres (14); show less...

University: Karolinska Institutet (42); Uppsala University (28); Lund University (24); University of Gothenburg (18); Umeå University (13); Stockholm School of Economics (5); show more...; Högskolan Dalarna (4); show less...

Language: English (52)

Research subject (UKÄ/SCB): Medical and Health Sciences (35); Natural sciences (3)

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