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  • Andersson-Sköld, Yvonne, 1957-, et al. (author)
  • Coal tar-containing asphalt : Resource or hazardous waste?
  • 2007
  • In: Journal of Industrial Ecology. - : Wiley-Blackwell. - 1088-1980 .- 1530-9290. ; 11:4, s. 99-116
  • Journal article (peer-reviewed)abstract
    • Coal tar was used in Sweden for the production of asphalt and for the drenching of stabilization gravel until 1973. The tar has high concentrations of polycyclic aromatic hydrocarbons (PAH), some of which may be strongly carcinogenic. Approximately 20 million tonnes of tar-containing asphalt is present in the public roads in Sweden. Used asphalt from rebuilding can be classified as hazardous waste according to the Swedish Waste Act. The cost of treating the material removed as hazardous waste can be very high due to the large amount that has to be treated, and the total environmental benefit is unclear. The transport of used asphalt to landfill or combustion will affect other environmental targets. The present project, based on three case studies of road projects in Sweden, evaluates the consequences of four scenarios for handling the material: reuse, landfill, biological treatment, and incineration. The results show that reuse of the coal tar-containing materials in new road construction is the most favorable alternative in terms of cost, material use, land use, energy consumption, and air emissions.
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  • Stockfelt, Leo, 1981, et al. (author)
  • Long-Term Exposure to Particulate Air Pollution, Black Carbon, and Their Source Components in Relation to Ischemic Heart Disease and Stroke
  • 2019
  • In: Journal of Environmental Health Perspectives. - Durham : National Institute of Environmental Health Sciences. - 0091-6765 .- 1552-9924. ; 127:10
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: Long-term exposure to particulate matter (PM) in ambient air has been associated with cardiovascular mortality, but few studies have considered incident disease in relation to PM from different sources.OBJECTIVES: We aimed to study associations between long-term exposure to different types of PM and sources, and incident ischemic heart disease (IHD) and stroke in three Swedish cities.METHODS: ), and black carbon (BC) from road wear, traffic exhaust, residential heating, and other sources in Gothenburg, Stockholm, and Umeå. Registry data for participants from four cohorts were used to obtain incidence of IHD and stroke for first hospitalization or death. We constructed time windows of exposure for same-year, 1- to 5-y, and 6- to 10-y averages preceding incidence from annual averages at residential addresses. Risk estimates were based on random effects meta-analyses of cohort-specific Cox proportional hazard models.RESULTS: exposure from residential heating.DISCUSSION: Few consistent associations were observed between different particulate components and IHD or stroke. However, long-term residential exposure to locally emitted BC from traffic exhaust was associated with stroke incidence. The comparatively low exposure levels may have contributed to the paucity of associations.
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  • Wallén-Mackenzie, Åsa, et al. (author)
  • Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function.
  • 2009
  • In: The Journal of neuroscience : the official journal of the Society for Neuroscience. - 1529-2401 .- 0270-6474. ; 29:7, s. 2238-51
  • Journal article (peer-reviewed)abstract
    • A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits of the adult brain contain a glutamatergic component, the nature of which has been difficult to assess because of the vast cellular abundance of glutamate. In this study, we wanted to determine the role of a restricted subpopulation of glutamatergic neurons within the forebrain, the Vglut2-expressing neurons, in neuronal circuitry of higher brain function. Vglut2 expression was selectively deleted in the cortex, hippocampus, and amygdala of preadolescent mice, which resulted in increased locomotor activity, altered social dominance and risk assessment, decreased sensorimotor gating, and impaired long-term spatial memory. Presynaptic VGLUT2-positive terminals were lost in the cortex, striatum, nucleus accumbens, and hippocampus, and a downstream effect on dopamine binding site availability in the striatum was evident. A connection between the induced late-onset, chronic reduction of glutamatergic neurotransmission and dopamine signaling within the circuitry was further substantiated by a partial attenuation of the deficits in sensorimotor gating by the dopamine-stabilizing antipsychotic drug aripiprazole and an increased sensitivity to amphetamine. Somewhat surprisingly, given the restricted expression of Vglut2 in regions responsible for higher brain function, our analyses show that VGLUT2-mediated neurotransmission is required for certain aspects of cognitive, emotional, and social behavior. The present study provides support for the existence of a neurocircuitry that connects changes in VGLUT2-mediated neurotransmission to alterations in the dopaminergic system with schizophrenia-like behavioral deficits as a major outcome.
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  • Result 1-10 of 147
Type of publication
journal article (54)
conference paper (47)
reports (28)
book chapter (10)
book (4)
artistic work (2)
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doctoral thesis (1)
research review (1)
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Type of content
peer-reviewed (86)
other academic/artistic (59)
pop. science, debate, etc. (2)
Author/Editor
Andersson, Karin, 19 ... (115)
Allard, Bert (29)
Torstenfelt, Börje (19)
Brynolf, Selma, 1984 (15)
Baldi, Francesco, 19 ... (12)
Fridell, Erik, 1963 (9)
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Olofsson, Ulla (8)
Granhag, Lena, 1974 (8)
Lindgren, Fredrik, 1 ... (7)
Grahn, Maria, 1963 (6)
Svensson, Erik, 1981 (6)
Wilewska-Bien, Magda ... (6)
Albinsson, Yngve, 19 ... (5)
Tullborg, Eva-Lena (5)
Nyström Claesson, An ... (5)
Höglund, Susanne (4)
Kipatsi, Heino (4)
Taljegård, Maria, 19 ... (3)
Andersson, Mats X., ... (3)
Ahlgren, Fredrik, 19 ... (3)
Sandelius, Anna Stin ... (3)
Johansson, Mikael (3)
Larsson, Sven Åke (3)
Eliasson, Lena (3)
Larsson, Lennart (3)
Torén, Kjell, 1952 (2)
Forsberg, Bertil (2)
Rosengren, Annika, 1 ... (2)
Andersson, Per (2)
Lager, Anton (2)
Larson, Sven Åke, 19 ... (2)
Landström, Ove (2)
Pedersen, Nancy L (2)
Tjellström, Henrik, ... (2)
Rönnerman, Karin, 19 ... (2)
Al-Khatib, Ahmad, 19 ... (2)
Andersson, Bengt A., ... (2)
Börjesson, Susanne, ... (2)
Alerby, Eva (2)
Arnqvist, Anders (2)
Beach, Dennis, 1956 (2)
Nilsson, Pernilla (2)
Olin-Scheller, Chris ... (2)
Williams, Pia, 1961 (2)
Rydberg, Jan, 1923 (2)
Leander, Karin (2)
Andersson-Sköld, Yvo ... (2)
Bengtsson, Monika (2)
Hansson, Julia, 1978 (2)
Landquist, Hanna, 19 ... (2)
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University
Chalmers University of Technology (129)
University of Gothenburg (20)
Karolinska Institutet (5)
Lund University (4)
Uppsala University (3)
Linnaeus University (3)
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Umeå University (2)
Stockholm University (2)
Linköping University (2)
IVL Swedish Environmental Research Institute (2)
Kristianstad University College (1)
Royal Institute of Technology (1)
Örebro University (1)
Jönköping University (1)
Mid Sweden University (1)
RISE (1)
Karlstad University (1)
Swedish University of Agricultural Sciences (1)
VTI - The Swedish National Road and Transport Research Institute (1)
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Language
English (137)
Swedish (10)
Research subject (UKÄ/SCB)
Engineering and Technology (93)
Natural sciences (69)
Social Sciences (16)
Medical and Health Sciences (9)
Humanities (2)

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