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- Aguirre, A., et al.
(författare)
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Variation in sexual expression in Jacaratia mexicana (Caricaceae) in southern Mexico : Frequency and relative seed performance of fruit-producing males
- 2007
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Ingår i: Biotropica. - 0006-3606 .- 1744-7429. ; 39:1, s. 79-86
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Tidskriftsartikel (refereegranskat)abstract
- Dioecy, the segregation of male and female structures among individuals, is widespread in tropical plants, encompassing 10-30 percent of species in some sites. In many cases, interindividual sex separation is not complete, as individual plants, although nominally dioecious, may produce both types of reproductive structures. A common form of this sexual variation is the production of female structures in otherwise male individuals, commonly referred to as fruiting males. Here we report the existence of fruiting males in the dioecious tropical tree Jacaratia mexicana (Caricaceae). We show that fruiting males can constitute up to 45 percent of all males in some populations of a tropical forest in Southern Mexico. In order to determine the functional significance of fruiting males for the breeding system of J. mexicana, we compared the relative performance of male- and female-borne seeds. Our results show that seeds from fruiting males are three times less likely to germinate and survive than seeds from female trees. Based on relative seed fitness data, and sex ratios in natural populations, we estimate that 6-15 percent of the genes contributed by fruiting males to the next generation are transmitted via ovules, meaning that morphological variation in gender is at least partially accompanied by functional gender variation. Finally, our seed fitness estimates for fruiting males suggest that fruiting males will not replace female plants in natural populations.
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- Garcia-Closas, Montserrat, et al.
(författare)
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Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
- 2008
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Ingår i: PLoS genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 4:4, s. e1000054-
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Tidskriftsartikel (refereegranskat)abstract
- A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9), mitogen-activated protein kinase 3 K1 (MAP3K1), 8q24, and lymphocyte-specific protein 1 (LSP1)) associated with breast cancer risk. We investigated whether the associations between these SNPs and breast cancer risk varied by clinically important tumor characteristics in up to 23,039 invasive breast cancer cases and 26,273 controls from 20 studies. We also evaluated their influence on overall survival in 13,527 cases from 13 studies. All participants were of European or Asian origin. rs2981582 in FGFR2 was more strongly related to ER-positive (per-allele OR (95%CI) = 1.31 (1.27-1.36)) than ER-negative (1.08 (1.03-1.14)) disease (P for heterogeneity = 10(-13)). This SNP was also more strongly related to PR-positive, low grade and node positive tumors (P = 10(-5), 10(-8), 0.013, respectively). The association for rs13281615 in 8q24 was stronger for ER-positive, PR-positive, and low grade tumors (P = 0.001, 0.011 and 10(-4), respectively). The differences in the associations between SNPs in FGFR2 and 8q24 and risk by ER and grade remained significant after permutation adjustment for multiple comparisons and after adjustment for other tumor characteristics. Three SNPs (rs2981582, rs3803662, and rs889312) showed weak but significant associations with ER-negative disease, the strongest association being for rs3803662 in TNRC9 (1.14 (1.09-1.21)). rs13281615 in 8q24 was associated with an improvement in survival after diagnosis (per-allele HR = 0.90 (0.83-0.97). The association was attenuated and non-significant after adjusting for known prognostic factors. Our findings show that common genetic variants influence the pathological subtype of breast cancer and provide further support for the hypothesis that ER-positive and ER-negative disease are biologically distinct. Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment.
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- Requies, J., et al.
(författare)
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Palladium-manganese catalysts supported on monolith systems for methane combustion
- 2008
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Ingår i: Applied Catalysis B. - : Elsevier BV. - 0926-3373 .- 1873-3883. ; 79:2, s. 122-131
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Tidskriftsartikel (refereegranskat)abstract
- Alumina-supported bimetallic and monometallic Mn and Pd monolithic catalysts were prepared and tested in methane combustion. Two different reactor configurations were adopted for catalyst testing, i.e. a fixed-bed laboratory-scale reactor and a pilot-plant reactor which allowed work at different temperatures and pressures. The results of catalyst performance showed that all bimetallic catalysts are considerably more stable for methane combustion than the monometallic palladium catalyst. With the aim to explain the relationship between activity-stability and structure and surface properties, the catalysts were characterized by TPO, XRD, XPS and ICP-AES. The high stability displayed by the bimetallic systems is attributed to the influence of manganese in retarding the decomposition of PdO into metallic palladium. Thus, it appears that manganese oxides inhibit PdO decomposition, as a consequence of the increase in oxygen mobility in the manganese oxide spinel phase.
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- Arias, Jaime M., et al.
(författare)
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Heat recovery and floating condensing in supermarkets
- 2006
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Ingår i: Energy and Buildings. - : Elsevier BV. - 0378-7788 .- 1872-6178. ; 38:2, s. 73-81
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Tidskriftsartikel (refereegranskat)abstract
- Supermarkets are great energy users in many countries. The potential for increased energy efficiency is large. One option is to utilize heat recovery (or heat reclaim) from condensers to heat the premises. Obviously this option is only interesting in relatively cold areas such as northern Europe, Canada, etc. An alternative to heat recovery is floating condensing pressure, which improves the coefficient of performance and decreases the energy consumption of the refrigeration system at lower outdoor temperature. Both heat recovery and floating condensing pressure can be utilized interchangeably depending on the heat requirements of the premises. A computer model that calculates the energy consumption in a supermarket with the possibility to simulate different system solutions for the refrigeration system has been developed at the Royal Institute of Technology, Department of Energy Technology. The software CyberMart is used in the present study to compare the potential of heat recovery and floating condensing in Swedish supermarkets. Measurements of different parameters such as temperatures, relative humidity and compressor power have been carried out in different supermarkets with heat recovery to validate the theoretical calculations. The present study shows that heating requirements can be covered completely by heat reclaim from the condenser. However, practical experiences show that installations are less efficient due to poor system solutions and/or control strategies. According to the results from CyberMart, the highest potential of energy saving is obtained from using a systems solution with both heat recovery and floating condensing.
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- Arias, Jaime M., et al.
(författare)
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Modelling and experimental validation of advanced refrigeration systems in supermarkets
- 2005
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Ingår i: Proceedings of the Institution of mechanical engineers. Part E, journal of process mechanical engineering. - : SAGE Publications. - 0954-4089 .- 2041-3009. ; 219:E2, s. 149-156
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Tidskriftsartikel (refereegranskat)abstract
- The effective use of energy and the replacement of CFC and HCFC refrigerants are two factors that have influenced the design and operation of refrigeration systems in supermarkets during recent years. The potential for increasing energy efficiency in refrigeration systems, indoor climate and refrigerated cabinets is large. Since the energy systems of a supermarket are relatively complex, improvements in one subsystem affect other systems, thus making analysis of potential improvements non-additive. A computer model, CyberMart, that predicts building heating and cooling loads, HVAC (heating, ventilation, and air conditioning), and refrigeration system performances of a supermarket, has been developed. The focus of the model is on energy use, environmental impact (TEWI), and life cycle cost (LCC) of the refngeration system. The refrigeration system solutions included in the model are: direct system, completely indirect system, partially indirect system, cascade system, parallel system with mechanical sub-cooling (where the refrigerant in the low-temperature system is sub-cooled with the brine of the intermediate temperature level), and district cooling (that cools the condenser of the refrigeration machines). Measurements of different parameters such as outdoor and indoor temperatures, relative humidity, and compressor power have been carried out in several stores to validate the model. A theoretical description of the model and results from the model and measurements are presented in this paper.
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