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Träfflista för sökning "(WFRF:(Fryze W)) srt2:(2006-2009)"

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1.	Calabresi, PA, et al. (author) The incidence and significance of anti-natalizumab antibodies: results from AFFIRM and SENTINEL 2007 In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 69:14, s. 1391-1403 Journal article (peer-reviewed)
2.	Bauer, J, et al. (author) Levetiracetam: a long-term follow-up study of efficacy and safety. 2006 In: Acta neurologica Scandinavica. - : Hindawi Limited. - 0001-6314 .- 1600-0404. ; 114:3, s. 169-76 Journal article (peer-reviewed)abstract OBJECTIVES: To evaluate the efficacy and safety of long-term add-on treatment with levetiracetam 1,000-4,000 mg/day. PATIENTS AND METHODS: In this multicenter, open-label follow-up study, 505 patients, from 10 European countries, who had benefited from previous add-on treatment with levetiracetam in a clinical trial or compassionate-use program were enrolled; 274 (54.3%) stayed to the end. Most then continued levetiracetam by prescription or in a named patient program, where it was not yet commercially available. Mean treatment duration was 1,045 days (range: 24 days to >7 years). Median daily dosage was 3,000 mg/day (range: 250-6,000 mg/day), with 250 (49.5%) patients receiving levetiracetam for >3 years. RESULTS: Median total and partial seizure frequency per week over the evaluation period were 0.8 and 0.7; seizure frequency per week was generally stable over time and remained low. There was a probability of 6.6% of remaining seizure-free for the first 3 years, and of 18.9% of having a seizure-free period of at least 3 years at any time. Most adverse events were mild or moderate and unrelated to study drug. Levetiracetam was well tolerated, and provided stable seizure control during long-term treatment.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Alonso, A. (1); Haddad, N. (1); Lee, L. (1); Ma, H. (1); Nielsen, J. (1); Young, C. (1); show more...; Green, B. (1); Gutierrez, A. (1); Wright, D. (1); Martin, J. (1); Kaufman, M (1); Kumar, S (1); Berger, T. (1); Meyer, R. (1); Martin, A. (1); Mares, J. (1); Gupta, V. (1); Hutchinson, M (1); Anderson, T. (1); Miller, J. (1); Pelayo, R. (1); Sobczynska, D. (1); Urbanek, K. (1); Haas, J (1); Goodman, A (1); King, J. (1); Garcia, E. (1); Taylor, L. (1); Hashimoto, S (1); Hillert, J (1); Olsson, T (1); Piehl, F (1); Adam, I (1); Esposito, F (1); Yaouanq, J (1); Comi, G (1); Wallstrom, E (1); Smith, T (1); Morgan, A (1); Miller, A (1); Schneider, K. (1); Fang, J. (1); Rother, J (1); Bowen, J. (1); Csiba, L. (1); Barber, A. (1); Achiron, A (1); Fredrikson, S (1); Andersson, M (1); Brown, M. (1); show less...

University: University of Gothenburg (1); Karolinska Institutet (1)

Language: English (2)

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