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- Andersson, Bodil, et al.
(author)
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Combining Keystroke Logging with Eye Tracking
- 2006
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In: Writing and Digital Media. - 1572-6304. - 0080448631 ; 17, s. 166-172
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Book chapter (peer-reviewed)abstract
- This chapter describes the successful development of a new methodology for studying on-line writing. The text-logging tool ScriptLog has been combined with the eyetracking technology iView X HED HT, in order to enhance the study of the interplay between writing, monitoring and revision. Data on the distribution of visual attention during writing help determining to what extent pauses are used for monitoring. The complexity of the experimental settings, and the expertise needed for interpreting the eye-tracking data make this a method suitable mainly for laboratory settings. The chapter also introduces an analysis tool that merges data from ScriptLog and iView and thus helps the researcher to organise and analyse the vast amount of data produced.
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- Andersson, Irene, 1978, et al.
(author)
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Endothelial dysfunction in growth hormone transgenic mice
- 2006
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In: Clinical Science. - 0143-5221 .- 1470-8736. ; 110:2, s. 217-25
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Journal article (peer-reviewed)abstract
- Acromegaly [overproduction of GH (growth hormone)] is associated with cardiovascular disease. Transgenic mice overexpressing bGH (bovine GH) develop hypertension and hypercholesterolaemia and could be a model for cardiovascular disease in acromegaly. The aims of the present study were to investigate the effects of excess GH on vascular function and to test whether oxidative stress affects endothelial function in bGH transgenic mice. We studied the ACh (acetylcholine)-induced relaxation response in aortic and carotid rings of young (9-11 weeks) and aged (22-24 weeks) female bGH transgenic mice and littermate control mice, without and with the addition of a free radical scavenger {MnTBAP [Mn(III)tetrakis(4-benzoic acid)porphyrin chloride]}. We also measured mRNA levels of eNOS (endothelial nitric oxide synthase) and EC-SOD (extracellular superoxide dismutase). Intracellular superoxide anion production in the vascular wall was estimated using a dihydroethidium probe. Carotid arteries from bGH transgenic mice had an impaired ACh-induced relaxation response (young, 46 +/- 7% compared with 69 +/- 8%; aged, 52 +/- 5% compared with 80 +/- 3%; P < 0.05), whereas endothelial function in aorta was intact in young but impaired in aged bGH transgenic mice. Endothelial dysfunction was corrected by addition of MnTBAP in carotid arteries from young mice and in aortas from aged mice; however, MnTBAP did not correct endothelial dysfunction in carotid arteries from aged bGH transgenic mice. There was no difference in intracellular superoxide anion production between bGH transgenic mice and control mice, whereas mRNA expression of EC-SOD and eNOS was increased in aortas from young bGH transgenic mice compared with control mice (P < 0.05). We interpret these data to suggest that bGH overexpression is associated with a time- and vessel-specific deterioration in endothelial function, initially caused by increased oxidative stress and later by other alterations in vascular function.
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- Hedekvist, Per Olof E, 1967, et al.
(author)
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Accurate time transfer utilizing the synchronization in an SDH-network
- 2006
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In: 2006 Optical Fiber Communication Conference, and the 2006 National Fiber Optic Engineers Conference; Anaheim, CA; United States; 5 March 2006 through 10 March 2006. - 9781557528032 ; 2006
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Conference paper (peer-reviewed)abstract
- A nationwide system for accurate time distribution is being developed, utilizing synchronization in an SDH-network. The first experimental results based on this technique are presented, performed on, but not limited to, STM-64.
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- Johansson, Håkan, 1979, et al.
(author)
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Error Computation for Parameter Identification Problems
- 2006
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In: GAMM (Gesellshaft für Angewandte Mathematik und Mechanik) Annual meering, Book of abstracts, March 27-31, 2006, Berlin, Germany. ; , s. 221-
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Conference paper (other academic/artistic)
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