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Träfflista för sökning "(WFRF:(Kauppinen J)) spr:eng srt2:(2000-2004)"

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1.	Kauppinen, T, et al. (author) Occupational exposure to carcinogens in the European Union 2000 In: Occupational and environmental medicine. - : BMJ. - 1351-0711. ; 57:1, s. 10-18 Journal article (peer-reviewed)
2.	Burstyn, I, et al. (author) Risk of fatal industrial accidents and death from other external causes among asphalt workers. 2004 In: Occup Environ Med. - 1470-7926. ; 61:1, s. 86-8 Journal article (peer-reviewed)
3.	Jin Lee, W, et al. (author) Mortality from lung cancer in workers exposed to sulfur dioxide in the pulp and paper industry. 2002 In: Journal of Environmental Health Perspectives. - 0091-6765 .- 1552-9924. ; 110, s. 991-995 Journal article (peer-reviewed)
4.	Mäkinen, Taija, et al. (author) Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. 2001 In: Nature Medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 7:2 Journal article (peer-reviewed)abstract The lymphatic vasculature transports extravasated tissue fluid, macromolecules and cells back into the blood circulation. Recent reports have focused on the molecular mechanisms regulating the lymphatic vessels. Vascular endothelial growth factor (VEGF)-C and VEGF-D have been shown to stimulate lymphangiogenesis and their receptor, VEGFR-3, has been linked to human hereditary lymphedema. Here we show that a soluble form of VEGFR-3 is a potent inhibitor of VEGF-C/VEGF-D signaling, and when expressed in the skin of transgenic mice, it inhibits fetal lymphangiogenesis and induces a regression of already formed lymphatic vessels, though the blood vasculature remains normal. Transgenic mice develop a lymphedema-like phenotype characterized by swelling of feet, edema and dermal fibrosis. They survive the neonatal period in spite of a virtually complete lack of lymphatic vessels in several tissues, and later show regeneration of the lymphatic vasculature, indicating that induction of lymphatic regeneration may also be possible in humans.
5.	Pulkkanen, KJ, et al. (author) The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice 2002 In: Cancer gene therapy. - : Springer Science and Business Media LLC. - 0929-1903 .- 1476-5500. ; 9:11, s. 908-916 Journal article (peer-reviewed)

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Type of publication: journal article (5)

Type of content: peer-reviewed (5)

Author/Editor: Boffetta, P (3); Kauppinen, T (3); Kromhout, H (2); Kogevinas, M (2); Sunyer, J (1); Kubo, H. (1); show more...; Alitalo, K (1); Young, R. (1); Hansen, J (1); Yla-Herttuala, S (1); Mäkinen, Taija (1); Ferro, G (1); Burstyn, I (1); Johansen, C (1); Stucker, I (1); Ahrens, W (1); Heederik, D (1); Shaham, J (1); Pearce, N (1); Vincent, R. (1); Järvholm, B (1); Persson, Bodil, 1950 ... (1); Fuxe, J. (1); Andersen, A (1); Plato, N (1); Pettersson, RF (1); Mirabelli, D (1); Partanen, T (1); Teschke, K. (1); Henneberger, P (1); Kauppinen, R (1); Pedersen, D (1); Colin, D (1); Svane, O (1); Langård, S (1); Bergdahl, I (1); Cenée, S (1); Hooiveld, M (1); Randem, B G (1); Jäppinen, P (1); Bergeret, A (1); Szadkowska-Stanczyk, ... (1); Kielkowski, D (1); Kishi, R (1); Facchini, LA (1); Nishikawa, S (1); Rehn, M (1); Karpanen, T (1); Jin Lee, W (1); Anddreassen Rix, B (1); show less...

University: Karolinska Institutet (2); Umeå University (1); Uppsala University (1); Linköping University (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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