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Träfflista för sökning "(WFRF:(Van Maerken T.)) srt2:(2010-2014)"

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1.	Kuchenbaecker, KB, et al. (author) Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers 2014 In: Breast cancer research : BCR. - : Springer Science and Business Media LLC. - 1465-542X .- 1465-5411. ; 16:6, s. 3416- Journal article (peer-reviewed)
2.	Mestdagh, P., et al. (author) An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours 2010 In: Oncogene. - : Springer Science and Business Media LLC. - 1476-5594 .- 0950-9232. ; 29:24, s. 3583-3592 Journal article (peer-reviewed)abstract Different classes of non-coding RNAs, including microRNAs, have recently been implicated in the process of tumourigenesis. In this study, we examined the expression and putative functions of a novel class of non-coding RNAs known as transcribed ultraconserved regions (T-UCRs) in neuroblastoma. Genome-wide expression pro. ling revealed correlations between specific T-UCR expression levels and important clinicogenetic parameters such as MYCN amplification status. A functional genomics approach based on the integration of multi-level transcriptome data was adapted to gain insights into T-UCR functions. Assignments of T-UCRs to cellular processes such as TP53 response, differentiation and proliferation were verified using various cellular model systems. For the first time, our results de. ne a T-UCR expression landscape in neuroblastoma and suggest widespread T-UCR involvement in diverse cellular processes that are deregulated in the process of tumourigenesis. Oncogene (2010) 29, 3583-3592; doi:10.1038/onc.2010.106; published online 12 April 2010

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Olsson, Håkan (1); Davidson, R. (1); Cook, J. (1); Hays, J. (1); Lee, A. (1); Friedman, E. (1); show more...; Benitez, J. (1); Dennis, J (1); Ellis, S. (1); Ejlertsen, B (1); James, P (1); Peterlongo, P (1); Olopade, OI (1); Menendez, M. (1); Khan, S (1); Berger, A. (1); Borg, A (1); Hamann, U (1); Andrulis, IL (1); Glendon, G (1); Schmidt, MK (1); Radice, P (1); Manoukian, S (1); Couch, FJ (1); Toland, AE (1); Simard, J (1); Jakubowska, A (1); Lubinski, J (1); Jaworska-Bieniek, K (1); Durda, K (1); Nevanlinna, H (1); Chenevix-Trench, G (1); Easton, DF (1); Giannini, G (1); Henriksson, Karin (1); Rihani, A (1); Platte, R (1); Eccles, D (1); Evans, DG (1); Buys, SS (1); Schmutzler, RK (1); Meindl, A (1); Wang-Gohrke, S (1); Wang, XS (1); van den Ouweland, AM ... (1); Ringnér, Markus (1); Borg, Åke (1); Cybulski, C (1); Teixeira, MR (1); Southey, M (1); show less...

University: Lund University (2); Karolinska Institutet (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

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