1. |
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- 2019
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Journal article (peer-reviewed)
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2. |
- Weinstein, John N., et al.
(author)
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The cancer genome atlas pan-cancer analysis project
- 2013
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In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:10, s. 1113-1120
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Research review (peer-reviewed)abstract
- The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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3. |
- Duev, Dmitry, et al.
(author)
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Planetary Radio Interferometry and Doppler Experiment (PRIDE) technique: A test case of the Mars Express Phobos fly-by
- 2016
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 593:A34
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Journal article (peer-reviewed)abstract
- The closest ever fly-by of the Martian moon Phobos, performed by the European Space Agency's Mars Express spacecraft, gives a unique opportunity to sharpen and test the Planetary Radio Interferometry and Doppler Experiments (PRIDE) technique in the interest of studying planet-satellite systems. Aims. The aim of this work is to demonstrate a technique of providing high precision positional and Doppler measurements of planetary spacecraft using the Mars Express spacecraft. The technique will be used in the framework of Planetary Radio Interferometry and Doppler Experiments in various planetary missions, in particular in fly-by mode. Methods. We advanced a novel approach to spacecraft data processing using the techniques of Doppler and phase-referenced very long baseline interferometry spacecraft tracking. Results. We achieved, on average, mHz precision (30 mu m/s at a 10 s integration time) for radial three-way Doppler estimates and sub-nanoradian precision for lateral position measurements, which in a linear measure (at a distance of 1.4 AU) corresponds to similar to 50 m.
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4. |
- Fu, L., et al.
(author)
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Microstructure and tribological properties of Cr3C2/Ni3Al composite materials prepared by hot isostatic pressing (HIP)
- 2017
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In: Materials and Design. - : Elsevier BV. - 1873-4197 .- 0264-1275. ; 115:115, s. 203-212
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Journal article (peer-reviewed)abstract
- Ni3Al-based composites with different Cr3C2 contents were fabricated by the hot isostatic pressing (HIP) technique.The microstructure, phase constitution, and tribological properties of the composites were investigated by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), transmission electron microscopy (TEM), and pin-on-disk wear tests. The results revealed that the strengthening phase is distributed homogeneously in the Ni3Al matrix. During the HIP process, M7C3 (M = Cr, Fe) is formed by diffusion of Fe, C, and Cr to the interface between the Cr3C2 particles and Ni3Al matrix. The diffusion process binds the phases and is important for improving the wear resistance of Cr3C2/Ni3Al composites. The wear measurements demonstrated that micro-cutting and fatigue wear are the dominant mechanisms for this tribological pair. The wear resistance of Cr3C2/Ni3Al composites is significantly improved by the addition of Cr3C2 particles.When the content of Cr3C2 is within a certain range, the wear resistance of Cr3C2/Ni3Al composites increases as the Cr3C2 content increases. However, the addition of excess Cr3C2 (for example, 24 vol% in this work) could lead to a decrease in the wear resistance of the composites. In addition, the average friction coefficients and wear of the counterpart decrease with increasing Cr3C2 addition.
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5. |
- Birkin, Jack E., et al.
(author)
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An ALMA/NOEMA survey of the molecular gas properties of high-redshift star-forming galaxies
- 2021
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 501:3, s. 3926-3950
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Journal article (peer-reviewed)abstract
- We have used ALMA and NOEMA to study the molecular gas reservoirs in 61 ALMA-identified submillimetre galaxies (SMGs) in the COSMOS, UDS, and ECDFS fields. We detect 12CO (Jup = 2-5) emission lines in 50 sources, and [C I](3P1 -3P0) emission in eight, at z = 1.2-4.8 and with a median redshift of 2.9±0.2. By supplementing our data with literature sources, we construct a statistical CO spectral line energy distribution and find that the 12CO line luminosities in SMGs peak at Jup ∼ 6, consistent with similar studies. We also test the correlations of the CO, [C I], and dust as tracers of the gas mass, finding the three to correlate well, although the CO and dust mass as estimated from the 3-mm continuum are preferable. We estimate that SMGs lie mostly on or just above the star-forming main sequence, with a median gas depletion timescale, tdep = Mgas/SFR, of 210±40 Myr for our sample. Additionally, tdep declines with redshift across z ∼ 1-5, while the molecular gas fraction, μgas = Mgas/M*, increases across the same redshift range. Finally, we demonstrate that the distribution of total baryonic mass and dynamical line width, Mbaryon-σ, for our SMGs is consistent with that followed by early-type galaxies in the Coma cluster, providing strong support to the suggestion that SMGs are progenitors of massive local spheroidal galaxies. On the basis of this, we suggest that the SMG populations above and below an 870-μm flux limit of S870 ∼ 5mJy may correspond to the division between slow and fast rotators seen in local early-type galaxies.
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6. |
- Feng, S., et al.
(author)
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Formation of In-Situ Dispersion Strengthening Particles in Cast FeCrAl Alloy
- 2010
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In: Journal of Iron and Steel Research International. - 1006-706X. ; 17:2, s. 74-78
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Journal article (peer-reviewed)abstract
- In order to fabricate dispersion strengthened alloys strengthened by submicron-sized or nano-sized stable particles through casting routes, understanding of the formation process of dispersion strengthening particles in metal melt is of significance. Thus, nano NiO and TiO2 particles were selected as reactant to form in-situ dispersion strengthening oxide particles in Fe20Cr5Al alloy. Nano NiO and TiO2 particle powder was separately dispersed into nano Ni powder first. The loose mixed nano powder was added in Fe20Cr5Al alloy melt when pouring the melt into mold. The study shows that nano NiO particles were not as effective as nano TiO2 particles in forming dispersion strengthening Al2O3 particles. The final diameters of dispersion strengthening oxide particles arose from nano TiO2 particles were of submicron. The Brownian collision of particles had caused this coarsening.
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7. |
- Feng, Yingkai, et al.
(author)
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Effect of Cr3C2 Content on the Microstructure and Wear Resistance of Fe3Al/Cr3C2 Composites
- 2022
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In: Coatings. - : MDPI AG. - 2079-6412. ; 12:12
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Journal article (peer-reviewed)abstract
- In this paper, an engine piston ring coating comprising composite material of Fe3Al and Cr3C2 mixed powder was prepared by laser cladding onto carbon structural steel. The microstructure and tribological properties of the cladding materials were investigated through X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), and wear tests. The influence mechanism of the Cr3C2 content in cladding powder was studied. During the process of wear, the soft Fe3Al/Fe2AlCr matrix is first ground off, and the hard Cr7C3 phase initially supports the abrasive surface before being worn away into hard particles, resulting in abrasive wear. With the increase in Cr3C2 content, the hardness of the cladding layer increases, the proportion of the Cr7C3 phase increases, and the morphology changes from a sparse network to a dense floccule. Of the cladding layers with different Cr3C2 content, the 15 wt.% Cr3C2 cladding layer had the lowest friction coefficient, and the 25 wt.% Cr3C2 cladding layer had the lowest wear rate. The low wear rate of the 25 wt.% Cr3C2 cladding layer can be attributed to the fact that adhesive wear does not easily occur and the fine microstructure of the strengthening phase, which facilitates better separation in the grinding surfaces.
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8. |
- Fu, L., et al.
(author)
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Effects of Cr3C2 content and temperature on sliding friction and wear behaviors of Cr3C2/Ni3Al composite materials
- 2018
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In: Wear. - : Elsevier BV. - 0043-1648. ; 414-415, s. 163-173
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Journal article (peer-reviewed)abstract
- Chromium carbide (Cr3C2)-reinforced Ni3Al matrix composites, which possess excellent high-temperature strength and wear resistance, are considered as potential high-temperature wear-resistant materials. In this study, effects of Cr3C2content on the friction and wear properties of Cr3C2/Ni3Al composites and their counterpart gray cast iron disks were investigated at different temperatures. The worn surface morphologies of the Cr3C2/Ni3Al composites and gray cast iron disks were analyzed to understand their wear mechanisms. The analysis results showed that in the Ni3Al matrix composites, a combination of abrasive wear and adhesive wear occurred at room temperature, whereas adhesive wear was severer at 200 °C. Furthermore, the optimum Cr3C2contents of the Cr3C2/Ni3Al composites were found to be 18 vol% and 12 vol% at room temperature and 200 °C, respectively. The volume loss of the composites increased with an increase in the fraction of the Cr3C2strengthening phase at 350 °C. The wear resistance of the gray cast iron disks decreased with an increase in temperature. In contrast, the wear resistance of the Ni3Al matrix composites increased with an increase in temperature. This increased wear resistance of the composites is attributed to the transformation of their wear mechanism with increasing temperature.
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9. |
- Garcaa-Fernandez, Angel F., et al.
(author)
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Gaussian implementation of the multi-Bernoulli mixture filter
- 2019
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In: FUSION 2019 - 22nd International Conference on Information Fusion.
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Conference paper (peer-reviewed)abstract
- This paper presents the Gaussian implementation of the multi-Bernoulli mixture (MBM) filter. The MBM filter provides the filtering (multi-target) density for the standard dynamic and radar measurement models when the birth model is multi-Bernoulli or multi-Bernoulli mixture. Under linear/Gaussian models, the single target densities of the MBM mixture admit Gaussian closed-form expressions. Murty's algorithm is used to select the global hypotheses with highest weights. The MBM filter is compared with other algorithms in the literature via numerical simulations.
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10. |
- Garcia, Angel, 1984, et al.
(author)
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A Poisson multi-Bernoulli mixture filter for coexisting point and extended targets
- 2021
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In: IEEE Transactions on Signal Processing. - 1941-0476 .- 1053-587X. ; 69, s. 2600-2610
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Journal article (peer-reviewed)abstract
- This paper proposes a Poisson multi-Bernoulli mixture (PMBM) filter for coexisting point and extended targets, i.e., for scenarios where there may be simultaneous point and extended targets. The PMBM filter provides a recursion to compute the multi-target filtering posterior based on probabilistic information on data associations, and single-target predictions and updates. In this paper, we first derive the PMBM filter update for a generalised measurement model, which can include measurements originated from point and extended targets. Second, we propose a single-target space that accommodates both point and extended targets and derive the filtering recursion that propagates Gaussian densities for single targets and gamma Gaussian inverse Wishart densities for extended targets. As a computationally efficient approximation of the PMBM filter, we also develop a Poisson multi-Bernoulli (PMB) filter for coexisting point and extended targets. The resulting filters are analysed via numerical simulations.
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