| 1. |
|
|
| 2. |
- Dahlin, Andreas, 1980
(author)
-
Nanoplasmonic Biosensors compatible with Artificial Cell Membranes
- 2008
-
Doctoral thesis (other academic/artistic)abstract
- Within life science, there is currently an intense search for novel techniques that enable efficient and reliable analysis of biomolecular interactions. Such methods have future applications within medical diagnostics and drug development, as well as within proteomic research in general. Lately, several concepts have emerged that are based on monitoring molecular binding to surfaces via optical, mechanical or electrical signal transduction. In particular, the plasmons associated with metallic nanoparticles are of interest since they offer a convenient way to monitor biomolecular interactions, also in a miniaturized format, by optical spectroscopy.This thesis describes the development of a biosensor based on the optical properties of nanoscale apertures in continuous metal films. The fabrication and characterization of the nanostructure is described, as well as surface modification protocols based on thiol chemistry for material-specific functionalization. In addition, an experimental setup for spectroscopy is presented together with data analysis algorithms for minimizing noise.It is emphasized that, from an experimental sensing perspective, nanoholes and nanoparticles have essentially the same plasmonic properties. However, the nanoholes offer several advantages because of the fact that the structure is physically different. In particular, it is shown how various artificial cell membranes can be spontaneously formed inside nanoholes. This makes the sensor compatible with studies of processes related to biological membranes. In this context, membrane-bound proteins are of special interest since they constitute a third of our genome and represent the target of half of the most common medical drugs. Potential future applications of the artificial membranes on the plasmonic nanostructures are discussed, with focus on probing transport across the membrane.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Dahl, Ingolf, 1950
(author)
-
How to measure the Mueller matrix of liquid-crystal cells
- 2001
-
In: Meas. Sci. Technol.. - 0957-0233. ; 12, s. 1938-1948
-
Journal article (peer-reviewed)abstract
- The Mueller matrix is the transfer matrix in the Stokes algebra that describes the polarization of natural light. This matrix is very versatile for the task of characterizing the optical properties of liquid-crystal cells, since it can be used for comparison with theoretical calculations, the determination of material parameters and the modelling of the cell as an optical building block for technological use. We have constructed a Mueller-matrix spectrometer, with the ability to perform fast, dynamic measurements of the Mueller matrix of small areas of liquid-crystal cells throughout the visible range. To illustrate the potential of the instrument, dynamic measurements on a ferroelectric-liquid-crystal cell are presented and analysed. The optical measurements indicate that there is an asymmetry between the up and the down state, tilted smectic layers and polarization reversal initiated at the boundaries.
|
|
| 6. |
- Desmaris, Vincent, 1977, et al.
(author)
-
Microfabrication Technology for All-Metal Sub-mm and THz Waveguide Receiver Components
- 2008
-
In: In Proceedings of The 19th International Symposium on Space Terahertz Technology, Groningen, 28-30 April, 2008, ed. W. Wild, Space Research Organization of the Netherlands (SRON). ; part I, s. 342-345
-
Conference paper (peer-reviewed)abstract
- A novel technology for manufacturing of micromachined all-metal waveguide circuits and structures for the frequency band from 200 up to 7000 GHz (Sub-Millimeter and THz) is presented. The waveguide circuits are formed using metal electroplating with preceding sputtering of a thin metal film seed layer over a photo-lithographically patterned thick SU-8 photo-resist. The process provides possibility of making 3-dimensional structures via facilitating of multi-level (layered) designs. Surface roughness of the THz waveguide structure was demonstrated to be below 0.1 µm. This technology was used to build a state-of-the art waveguide balanced 1.3 THz Hot Electron Bolometer mixer and other application for radio astronomy instrumentation.
|
|
| 7. |
- Mamontov, Eugen, 1955, et al.
(author)
-
Asymptotic trajectory matching in self-navigation of autonomous manless interceptors: Nonsearch method and a formulation of the functional optimization of the stability of random systems
- 2006
-
In: Proc. 5th MATHMOD Vienna Conf., 8-10 February, 2006 (Vienna Univ. of Technol., Vienna, Austria). - 3901608303 ; 2
-
Conference paper (peer-reviewed)abstract
- In the field of self-navigation autonomous manless robots there is a noticeable interest to the robot-based target-interception problem. The interceptor trajectory is usually determined by search-based optimization algorithms. In contrast to this, the present work treats the interception as asymptotic trajectory matching and introduces a nonsearch method for the interceptor trajectory. This method is substantially simpler than the well-known proportional navigation and requires very limited computing resources. The latter feature makes the proposed method especially suitable to the interceptors based on embedded onboard computers and civil applications. An example of the latter discussed in the work is the protection of the infrastructure components against intended or unintended attacks. In a general case when parameters of the interceptor are random, the new method leads to a formulation of a new problem in stochastic optimization, namely the functional optimization of (the so-called targetal) stability of the interceptor trajectory. Certain aspects of a practical implementation of the new systems are analyzed. The work proposes the basic physical principle and schemes for innovative sensors which can make the interceptors truly autonomous, in particular, fully GPS-free. A list of the fundamental and applied topics for future research is also suggested.
|
|
| 8. |
- André, Alann, et al.
(author)
-
Finite element delamination study of a notched composite plate under flexural loads
- 2009
-
In: ICCM-17, 17th International Conference on Composite Materials, Edinburgh, UK. - London : IOM Communications.
-
Conference paper (peer-reviewed)abstract
- The delamination process in notched composite plates under flexural loading has been investigated using finite element analysis. Cohesive elements implemented in the commercial finite element package ABAQUS have been used in the region around the drilled-hole, and positioned between layers where delamination was observed during experiments presented in an accompanying paper. The delamination initiation and subsequent propagation was studied between the layers at the tension side separately and simultaneously. For all FE models, the load displacement curve was in good agreement with the one from experiments. However, the amount of damage reported from the fractography study was more extensive than that predicted by the models. Finally, it was shown that the models with only one cohesive layer show significantly different results to that of the model with four cohesive layers in terms of size of the degradation area.
|
|
| 9. |
|
|
| 10. |
- Azadian, Saied
(author)
-
Aspects of precipitation in alloy Inconel 718
- 2004
-
Doctoral thesis (other academic/artistic)abstract
- A study was made of the microstructure of the Ni-base alloy Inconel 718 with emphasis on the precipitation and stability of intermetallic phases as affected by heat treatments. In addition the effect of the precipitation on selected mechanical properties namely hardness, creep notch sensitivity and hot ductlity were investigated. The materials studied were a spray-formed version and three wrought versions of the alloy. The spray-formed version of the alloy was of interest since it exhibited a superior compositional homogeneity to more conventional forms of the alloy. To characterise the precipitation kinetics and to determine the associated hardening, a series of isothermal ageing treatments were carried out on both spray-formed and ring rolled material at selected temperatures between 600°C and 1025°C for up to 100h. The results were presented in the form of TTH diagrams for the two alloys. The heat treated specimens were then studied using optical microscopy, scanning electron microscopy and transmission electron microscopy. Where possible these were supplemented with quantitative metallographic measurements of volume fraction and precipitates size.The three main intermetallic precipitation phases in IN 718 are (i) gamma’ having a composition Ni3(Al,Ti), a cubic crystal structure and cubic or spherical particle shape (ii) gamma” having a composition Ni3Nb, a bct crystal structure and a lens-like disc shape (iii)delta having composition Ni3Nb, an orthorhombic crystal structure and forming as grain boundary particles and films as well as thin plates extending long distances into the grains. In thermomechanically processed material the delta-phase can also occur as shorter platelets and particles resulting from fragmentation of the original plates. In this work the rates of precipitation and the temperature ranges of their existence were determined qualitatively. Moreover the coarsening of the ganmma" precipitates was determined quantitatively. The kinetics of precipitation and dimensional coarsening of the delta-phase were also established quantitatively. Similarly, the dissolution kinetics of the delta-phase were measured in the spray-formed and three wrought versions of the alloy leading to a determination of the effect of Nb-content on the delta solvus temperature. After a standard heat treatment, the spray-formed IN 718 was found to be creep notch sensitive according to an SAE-AMS standard rupture test. It was found that notch ductility could be restored to the alloy by inserting a delta-phase precipitation treatment at 875°C-900°C prior to the standard heat treatment. This could be attributed to the formation of a more favourable delta-phase morphology than that formed during the solution treatment at 954°C in the standard heat treatment cycle. A study was made of high temperature tensile properties of a wrought version of IN 718 in particular in relation to the problem of hot cracking in repair welding. Measurements were made of the strength loss temperature on heating and the strength and ductility return temperatures on cooling. These properties provide an indication of the sensitivity of the alloy to hot cracking due to liquation. The tests were made on the alloy after various heat treatments designed to produce microstructures with two different grain sizes with and without delta-phase precipitation. Hot tensile tests were also performed on the in-situ solidified alloy in order to describe the weld metal ductility and properties. The grain size and the presence of large fractions of delta-phase precipitated at 900°C had only small effects on the strength loss temperature and brittle-ductile transition of the alloy. On the other hand, a small fraction of delta-phase precipitated in the grain boundaries at 960°C reduced the brittle-ductile transition temperature significantly. It is proposed that the reduction was associated with interaction between the grain boundary delta-phase and grain boundary boron segregation that was observed in all the heat treated materials.
|
|
