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Träfflista för sökning "L773:0065 2598 OR L773:0306478706 OR L773:9780306478703 srt2:(1979)"

Search: L773:0065 2598 OR L773:0306478706 OR L773:9780306478703 > (1979)

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1.
  • Hamberg, U, et al. (author)
  • Human kininogen from Cohns Fraction IV : comparisons of antigenicity and multiple forms
  • 1979
  • In: Advances in Experimental Medicine and Biology. - 0065-2598 .- 2214-8019. ; 120B, s. 173-183
  • Journal article (peer-reviewed)abstract
    • Kininogen was isolated from Cohns fraction IV by DEAE-chromatography, gel filtration and ammonium sulphate precipitation. Immunologically pure kininogen was prepared by removal of protein impurities using specific immunoadsorbents with Sepharose-bound antibody. Anti-kininogen serum was raised in rabbits against the pure antigen. Comparison with anti-kininogen sera prepared with the biologically active LMW antigen from whole plasma suggested antigenic identity by double immunodiffusion analysis. The Cohn-kininogen was shown to contain mainly two components (85%) in about equal amounts focusing with peaks at pI 4.2 (42%) and pI 4.3 (43%). These represent apparently structurally altered forms of the native plasma kininogen focusing at pI 4.5-4.6 (54%), which occurred as a minor component (13%).
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Andersson, A (1)
Agren, A (1)
Nilsson, B (1)
Sandler, S (1)
Petersson, B (1)
Hellerström, C (1)
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Syvanen, Ann-Christi ... (1)
Hamberg, U (1)
Karkkainen, T (1)
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University
Uppsala University (2)
Language
English (2)
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