| 1. |
- Lubberink, Mark, et al.
(author)
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Quantification aspects of patient studies with 52Fe in positron emission tomography
- 1999
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In: Applied Radiation and Isotopes. - 0969-8043 .- 1872-9800. ; 51:6, s. 707-715
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Journal article (peer-reviewed)abstract
- Quantification accuracy in positron emission tomography (PET) using non-pure positron emitters, such as 52Fe, may be influenced by gamma radiation emitted in the decay of these isotopes. High-energy positrons, emitted in the decay of the 52Fe-daughter 52mMn, also affect the quantification accuracy. A specific problem of the 52Fe/52mMn decay chain in vivo is that the kinetics of iron and manganese are different, and that PET cannot discriminate between the two nuclides. The effect of the decay properties of 52Fe/52mMn on the performance of PET was investigated using phantoms. Minor degradation in PET performance was found for 52Fe/52mMn compared to the pure low-energy positron emitter 18F. A method is presented to obtain a correction factor for the 52mMn radioactivity in blood. A model for correction of 52mMn-radioactivity in organs, based on existing data on manganese kinetics, is given. The presented corrections are discussed and illustrated in a patient study.
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| 2. |
- Olsson, Sara, 1970-, et al.
(author)
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Ammonium tartrate as an ESR dosimeter material
- 1999
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In: Applied Radiation and Isotopes. - 0969-8043 .- 1872-9800. ; 50:5, s. 955-965
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Journal article (peer-reviewed)abstract
- This study is one step in the search for an ESR dosimeter material with a higher signal intensity than the commonly used l-α-alanine, to be useful in the clinical dose range (approximately 0.1–20 Gy). The substance ammonium tartrate was found and investigated regarding signal intensity, radical stability, dose response and dose resolution. The ESR signal intensity of ammonium tartrate was shown to be more than twice the intensity of the alanine signal. The data indicate that an unstable radiation induced radical contributes to the ESR signal initially; after a couple of hours it has converted to a secondary radical which has a decay slow enough to be considered stable during the first two weeks after irradiation. Ammonium tartrate has a linear dose response in the investigated range of 0.5–4000 Gy and a dose resolution of 0.1 Gy at the 0.5 Gy level where, as a comparison, the corresponding value for alanine is 0.3 Gy. We thus find the substance suitable for clinical dosimetry.
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| 3. |
- Olsson, Sara, et al.
(author)
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Dose response and fading characteristics of an Alanine-Agarose gel
- 1996
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In: Applied Radiation and Isotopes. - 0969-8043 .- 1872-9800. ; 47:11-12, s. 1211-1217
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Journal article (peer-reviewed)abstract
- The dose response of an alanine-agarose gel, analyzed by ESR spectrometry, and the stability of the radiation-induced free radicals have been investigated. The stability of the ESR signal is higher for dosimeter samples analyzed at 77 K than for dried samples, analyzed at room-temperature. The dose response is linear to within ±2% in the absorbed dose interval 2–100 Gy. The variations in spectral line shape were analyzed at temperatures between 77 and 270 K. The experimental ESR spectrum at 77 K was compared with a simulated spectrum of polycrystals of L-α-alanine.
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| 4. |
- Tolmachev, Vladimir, et al.
(author)
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Diffusion based separation methods : Dry distillation of zinc, cadmium and mercury isotopes from irradiated targets
- 1997
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In: Applied Radiation and Isotopes. - 0969-8043 .- 1872-9800. ; 48:5, s. 565-569
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Journal article (peer-reviewed)abstract
- Diffusion-based separation methods allow the extraction of produced radionuclides with a low loss of target material, which is of special importance when enriched target material is used. We present a simple, non-destructive and rapid method to separate radioactive isotopes of IIB group elements (zinc, cadmium and mercury) from IB group metal targets irradiated with protons. Irradiated target foils were heated to a temperature 20°C below the melting point of the target materials. During these conditions at least 90% of the desired radioactivity was evaporated with negligible loss of target material. Separation time was 15 min for mercury, 60 min for cadmium and 120 min for zinc.
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| 5. |
- Tolmachev, Vladimir, et al.
(author)
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Production of 61Cu from a natural nickel target
- 1998
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In: Applied Radiation and Isotopes. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0969-8043 .- 1872-9800. ; 49:1-2, s. 79-81
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Journal article (peer-reviewed)
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| 6. |
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| 7. |
- Dance, D R, et al.
(author)
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Breast dosimetry
- 1999
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In: Applied Radiation and Isotopes. - 0969-8043 .- 1872-9800. ; 50, s. 185-203
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Journal article (peer-reviewed)
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