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Träfflista för sökning "L773:1478 6419 OR L773:1478 6427 srt2:(2015-2019)"

Search: L773:1478 6419 OR L773:1478 6427 > (2015-2019)

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1.
  • Gomaa, Mohamed N., et al. (author)
  • Antibacterial effect of the red sea soft coral Sarcophyton trocheliophorum
  • 2016
  • In: Natural Product Research. - : Informa UK Limited. - 1478-6419 .- 1478-6427. ; 30:6, s. 729-734
  • Journal article (peer-reviewed)abstract
    • The marine soft corals Sarcophyton trocheliophorum crude extracts possessed antimicrobial activity towards pathogenic bacterial strains, i.e. Bacillus cereus, Salmonella typhi, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. Bioassay-guided fractionation indicated that the antimicrobial effect was due to the presence of terpenoid bioactive derivatives. Further biological assays of the n-hexane fractions were carried out using turbidity assay, inhibition zone assay and minimum inhibitory concentration for investigating the growth-inhibition effect towards the Gram-positive and Gram-negative bacteria. The fractions were screened and the structure of the isolated compound was justified by interpretation of the spectroscopic data, mainly mass spectrometry (GC-MS). The structure was assigned as (5S)-3-[(3E,5S)-5-hydroxy-3-hepten-6-yn-1-yl]-5-methyl-2(5H)-furanone and was effective at concentrations as low as 0.20mg/mL. The above findings, in the course of our ongoing research on marine products, may implicate that the profound anti-microbial activity of the S. trocheliophorum soft corals, inhabiting the red sea reefs, is attributed to the presence of growth-inhibiting secondary metabolites mainly terpenoids.
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2.
  • Zubair, Muhammad, et al. (author)
  • Promotion of wound healing by Plantago major L. leaf extracts : Ex-vivo experiments confirm experiences from traditional medicine
  • 2016
  • In: Natural Product Research. - : Informa UK Limited. - 1478-6419 .- 1478-6427. ; 30:5, s. 622-624
  • Journal article (peer-reviewed)abstract
    • The wound-healing properties of Plantago major L. (plantain) were evaluated using an ex-vivo porcine wound-healing model. Ethanol- and water-based extracts were prepared from greenhouse-grown and freeze-dried leaves of P. major. Both types of extracts stimulated wound healing in porcine skin, but the ethanol-based extracts had a somewhat stronger effect. A concentration of 1.0 mg/mL (on dry weight basis) produced the best results for both types of extracts.
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