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Träfflista för sökning "L773:1570 0232 OR L773:1873 376X srt2:(1995-1999)"

Search: L773:1570 0232 OR L773:1873 376X > (1995-1999)

  • Result 1-2 of 2
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1.
  • Delgado, C, et al. (author)
  • Analytical partitioning of poly(ethyleneglycol)-modified proteins
  • 1997
  • In: Journal of chromatography. B. - 1570-0232 .- 1873-376X. ; 692, s. 263-272
  • Journal article (peer-reviewed)abstract
    • Covalently grafting proteins with varying numbers (n) of poly(ethylene glycol) molecules (PEGs) often enhances their biomedical and industrial usefulness. Partition between the phases in aqueous polymer two-phase systems can be used to rapidly characterize polymer-protein conjugates in a manner related to various enhancements. The logarithm of the partition coefficient (K) approximates linearity over the range 0
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2.
  • Carlsson, Björn, et al. (author)
  • Solid-phase extraction with end-capped C2 columns for the routine measurement of racemic citalopram and metabolites in plasma by high-performance liquid chromatography
  • 1997
  • In: Journal of Chromatography B: Biomedical Sciences and Applications. - 1570-0232. ; 702:1-2, s. 234-239
  • Journal article (peer-reviewed)abstract
    • An assay based on solid-phase extraction followed by high-performance liquid chromatography (HPLC) was developed for the measurement of citalopram and its main metabolites desmethylcitalopram and didesmethylcitalopram. The best extraction procedure was performed with end-capped C2 column utilising secondary silanol interactions to obtain clean extract. The HPLC analysis was done on a phenyl column with a mobile phase without any amine additives. Fluorescence detection gave a limit of detection of 0.8 nmol/l plasma for the compounds analysed.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Delgado, C. (1)
Malmsten, M (1)
Carlsson, Björn (1)
Norlander, Björn (1)
Van Alstine, JM (1)
University
Linköping University (1)
RISE (1)
Language
English (2)
Year
1997 (2)

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