| 1. |
- Adamo, Angela, et al.
(author)
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Star cluster formation in the most extreme environments: Insights from the HiPEEC survey
- 2020
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In: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 499:3, s. 3267-3294
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Journal article (peer-reviewed)abstract
- We present the Hubble imaging Probe of Extreme Environments and Clusters (HiPEEC) survey. We fit HST NUV to NIR broad-band and H α fluxes to derive star cluster ages, masses, and extinctions and determine the star formation rate (SFR) of six merging galaxies. These systems are excellent laboratories to trace cluster formation under extreme gas physical conditions, rare in the local Universe, but typical for star-forming galaxies at cosmic noon. We detect clusters with ages of 1-500 Myr and masses that exceed 107 M☉. The recent cluster formation history and their distribution within the host galaxies suggest that systems such as NGC 34, NGC 1614, and NGC 4194 are close to their final coalescing phase, while NGC 3256, NGC 3690, and NGC 6052 are at an earlier/intermediate stage. A Bayesian analysis of the cluster mass function in the age interval 1-100 Myr provides strong evidence in four of the six galaxies that an exponentially truncated power law better describes the observed mass distributions. For two galaxies, the fits are inconclusive due to low number statistics. We determine power-law slopes β ∼ −1.5 to −2.0 and truncation masses, Mc, between 106 and a few times 107 M☉, among the highest values reported in the literature. Advanced mergers have higher Mc than early/intermediate merger stage galaxies, suggesting rapid changes in the dense gas conditions during the merger. We compare the total stellar mass in clusters to the SFR of the galaxy, finding that these systems are among the most efficient environments to form star clusters in the local Universe.
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| 2. |
- Adamo, Angela, et al.
(author)
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Star Clusters Near and Far Tracing Star Formation Across Cosmic Time
- 2020
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In: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 216:4
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Research review (peer-reviewed)abstract
- Star clusters are fundamental units of stellar feedback and unique tracers of their host galactic properties. In this review, we will first focus on their constituents, i.e. detailed insight into their stellar populations and their surrounding ionised, warm, neutral, and molecular gas. We, then, move beyond the Local Group to review star cluster populations at various evolutionary stages, and in diverse galactic environmental conditions accessible in the local Universe. At high redshift, where conditions for cluster formation and evolution are more extreme, we are only able to observe the integrated light of a handful of objects that we believe will become globular clusters. We therefore discuss how numerical and analytical methods, informed by the observed properties of cluster populations in the local Universe, are used to develop sophisticated simulations potentially capable of disentangling the genetic map of galaxy formation and assembly that is carried by globular cluster populations.
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| 3. |
- Adamo, Angela, 1981-, et al.
(author)
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The ages and metallicities of the globular clusters in the Sparkler
- 2023
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In: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 525:1, s. L6-L10
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Journal article (peer-reviewed)abstract
- JWST observations of the strongly lensed galaxy the Sparkler have revealed a population of gravitationally bound globular cluster (GC) candidates. Different analyses have resulted in broadly similar ages but significantly different metallicities, questioning the assembly history that has led to the formation of such a population. In this letter, we reanalyse the two sets of photometry available in the literature with the code MCMAME especially tailored to fit physical properties of GCs. We find the ages and metallicities from both data sets are consistent within 1σ uncertainties. A significant group of GCs is consistent with being old and metal poor ([Fe/H] ∼ −1.7). For this group, the ages do not converge, hence, we conclude that they are definitively older than 1 Gyr and can be as old as the age of the Universe. The remaining GCs have younger ages and a metallicity spread. The ages and metallicities distribution of GCs in the Sparkler are consistent with those observed in Local Group’s galaxies at similar lookback times. Comparing with predictions from E-MOSAICS simulations we confirm that the Sparkler GC population traces the self-enrichment history of a galaxy which might become a few times 109 M⊙ massive system at redshift z = 0.
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| 4. |
- Ballesteros-Paredes, Javier, et al.
(author)
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From Diffuse Gas to Dense Molecular Cloud Cores
- 2020
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In: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 216:5
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Research review (peer-reviewed)abstract
- Molecular clouds are a fundamental ingredient of galaxies: they are the channels that transform the diffuse gas into stars. The detailed process of how they do it is not completely understood. We review the current knowledge of molecular clouds and their substructure from scales similar to 1kpc down to the filament and core scale. We first review the mechanisms of cloud formation from the warm diffuse interstellar medium down to the cold and dense molecular clouds, the process of molecule formation and the role of the thermal and gravitational instabilities. We also discuss the main physical mechanisms through which clouds gather their mass, and note that all of them may have a role at various stages of the process. In order to understand the dynamics of clouds we then give a critical review of the widely used virial theorem, and its relation to the measurable properties of molecular clouds. Since these properties are the tools we have for understanding the dynamical state of clouds, we critically analyse them. We finally discuss the ubiquitous filamentary structure of molecular clouds and its connection to prestellar cores and star formation.
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| 5. |
- Benatar, Michael, et al.
(author)
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Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01) : a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial
- 2024
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In: Lancet Neurology. - : Elsevier. - 1474-4422 .- 1474-4465. ; 23:7, s. 687-699
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Journal article (peer-reviewed)abstract
- Background: Amyotrophic lateral sclerosis is a progressive neurodegenerative disorder leading to muscle weakness and respiratory failure. Arimoclomol, a heat-shock protein-70 (HSP70) co-inducer, is neuroprotective in animal models of amyotrophic lateral sclerosis, with multiple mechanisms of action, including clearance of protein aggregates, a pathological hallmark of sporadic and familial amyotrophic lateral sclerosis. We aimed to evaluate the safety and efficacy of arimoclomol in patients with amyotrophic lateral sclerosis.Methods: ORARIALS-01 was a multinational, randomised, double-blind, placebo-controlled, parallel-group trial done at 29 centres in 12 countries in Europe and North America. Patients were eligible if they were aged 18 years or older and met El Escorial criteria for clinically possible, probable, probable laboratory-supported, definite, or familial amyotrophic lateral sclerosis; had an ALS Functional Rating Scale-Revised score of 35 or more; and had slow vital capacity at 70% or more of the value predicted on the basis of the participant's age, height, and sex. Patients were randomly assigned (2:1) in blocks of 6, stratified by use of a stable dose of riluzole or no riluzole use, to receive oral arimoclomol citrate 1200 mg/day (400 mg three times per day) or placebo. The Randomisation sequence was computer generated centrally. Investigators, study personnel, and study participants were masked to treatment allocation. The primary outcome was the Combined Assessment of Function and Survival (CAFS) rank score over 76 weeks of treatment. The primary outcome and safety were analysed in the modified intention-to-treat population. This trial is registered with ClinicalTrials.gov, NCT03491462, and is completed.Findings: Between July 31, 2018, and July 17, 2019, 287 patients were screened, 245 of whom were enrolled in the trial and randomly assigned. The modified intention-to-treat population comprised 239 patients (160 in the arimoclomol group and 79 in the placebo group): 151 (63%) were male and 88 (37%) were female; mean age was 57·6 years (SD 10·9). CAFS score over 76 weeks did not differ between groups (mean 0·51 [SD 0·29] in the arimoclomol group vs 0·49 [0·28] in the placebo group; p=0·62). Cliff's delta comparing the two groups was 0·039 (95% CI –0·116 to 0·194). Proportions of participants who died were similar between the treatment groups: 29 (18%) of 160 patients in the arimoclomol group and 18 (23%) of 79 patients in the placebo group. Most deaths were due to disease progression. The most common adverse events were gastrointestinal. Adverse events were more often deemed treatment-related in the arimoclomol group (104 [65%]) than in the placebo group (41 [52%]) and more often led to treatment discontinuation in the arimoclomol group (26 [16%]) than in the placebo group (four [5%]).Interpretation: Arimoclomol did not improve efficacy outcomes compared with placebo. Although available biomarker data are insufficient to preclude future strategies that target the HSP response, safety data suggest that a higher dose of arimoclomol would not have been tolerated.Funding: Orphazyme.
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| 6. |
- Bortolini, Giacomo, 1996-, et al.
(author)
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The spatially resolved star formation history of the dwarf spiral galaxy NGC 5474
- 2024
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In: Monthly notices of the Royal Astronomical Society. - 0035-8711 .- 1365-2966. ; 527:3, s. 5339-5355
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Journal article (peer-reviewed)abstract
- We study the resolved stellar populations and derive the star formation history of NGC 5474, a peculiar star-forming dwarf galaxy at a distance of ∼7 Mpc, using Hubble Space Telescope Advanced Camera for Surveys data from the Legacy Extragalactic UV Survey (LEGUS) programme. We apply an improved colour–magnitude diagram fitting technique based on the code SFERA and use the latest PARSEC–COLIBRI stellar models. Our results are the following. The off-centre bulge-like structure, suggested to constitute the bulge of the galaxy, is dominated by star formation (SF) activity initiated 14 Gyr ago and lasted at least up to 1 Gyr ago. Nevertheless, this component shows clear evidence of prolonged SF activity (lasting until ∼10 Myr ago). We estimate the total stellar mass of the bulge-like structure to be (5.0 ± 0.3) × 108 M⊙. Such a mass is consistent with published suggestions that this structure is in fact an independent system orbiting around and not within NGC 5474’s disc. The stellar overdensity located to the South–West of the bulge-like structure shows a significant SF event older than 1 Gyr, while it is characterized by two recent peaks of SF, around ∼10 and ∼100 Myr ago. In the last Gyr, the behaviour of the stellar disc is consistent with what is known in the literature as ‘gasping’. The synchronized burst at 10–35 Myr in all components might hint to the recent gravitational interaction between the stellar bulge-like structure and the disc of NGC 5474.
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| 7. |
- Calzetti, Daniela, et al.
(author)
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Dust-buried Compact Sources in the Dwarf Galaxy NGC 4449
- 2023
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In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 946:1
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Journal article (peer-reviewed)abstract
- Multiwavelength images from the Hubble Space Telescope covering the wavelength range 0.27–1.6 μm show that the central area of the nearby dwarf galaxy NGC 4449 contains several tens of compact sources that are emitting in the hydrogen recombination line Paβ (1.2818 μm) but are only marginally detected in Hα (0.6563 μm) and undetected at wavelengths λ ≤ 0.55 μm. An analysis of the spectral energy distributions (SEDs) of these sources indicates that they are likely relatively young stellar clusters heavily attenuated by dust. The selection function used to identify the sources prevents meaningful statistical analyses of their age, mass, and dust extinction distributions. However, these cluster candidates have ages ∼5–6 Myr and AV > 6 mag, according to their SED fits, and are extremely compact, with typical deconvolved radii of 1 pc. The dusty clusters are located at the periphery of the dark clouds within the galaxy and appear to be partially embedded. Density and pressure considerations indicate that the H ii regions surrounding these clusters may be stalled, and that pre-supernova (pre-SN) feedback has not been able to clear the clusters of their natal cocoons. These findings are in potential tension with existing models that regulate star formation with pre-SN feedback, since pre-SN feedback acts on short timescales, ≲4 Myr, for a standard stellar initial mass function. The existence of a population of dusty stellar clusters with ages >4 Myr, if confirmed by future observations, paints a more complex picture for the role of stellar feedback in controlling star formation.
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| 8. |
- Calzetti, Daniela, et al.
(author)
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Revisiting Attenuation Curves : The Case of NGC 3351
- 2021
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In: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 913:1
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Journal article (peer-reviewed)abstract
- Multiwavelength images from the far-UV (similar to 0.15 mu m) to the submillimeter of the central region of the galaxy NGC 3351 are analyzed to constrain its stellar populations and dust attenuation. Despite hosting a similar to 1 kpc circumnuclear starburst ring, NGC 3351 deviates from the IRX-beta relation, the relation between the infrared-to-UV luminosity ratio and the UV continuum slope beta that other starburst galaxies follow. To understand the reason for the deviation, we leverage the high angular resolution of archival near-UV-to-near-IR Hubble Space Telescope images to divide the ring into similar to 60-180 pc size regions and model each individually. We find that the UV slope of the combined intrinsic (dust-free) stellar populations in the central region is redder than what is expected for a young model population. This is due to the region's complex star formation history, which boosts the near-UV emission relative to the far-UV. The resulting net attenuation curve has a UV slope that lies between those of the starburst attenuation curve (Calzetti et al. 2000) and the Small Magellanic Cloud extinction curve; the total-to-selective attenuation value, R'(V) = 4.93, is larger than both. As found for other star-forming galaxies, the stellar continuum of NGC 3351 is less attenuated than the ionized gas, with E(B - V)(star) = 0.40 E(B - V)(gas). The combination of the red intrinsic stellar population and the new attenuation curve fully accounts for the location of the central region of NGC 3351 on the IRX-beta diagram. Thus, the observed characteristics result from the complex mixture of stellar populations and dust column densities in the circumnuclear region. Despite being a sample of one, these findings highlight the difficulty of defining attenuation curves of general applicability outside the regime of centrally concentrated starbursts.
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| 9. |
- Chen, Boquan, et al.
(author)
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Discovery of new stellar groups in the Orion complex : Towards a robust unsupervised approach
- 2020
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In: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 643
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Journal article (peer-reviewed)abstract
- We test the ability of two unsupervised machine learning algorithms, EnLink and Shared Nearest Neighbor (SNN), to identify stellar groupings in the Orion star-forming complex as an application to the 5D astrometric data from Gaia DR2. The algorithms represent two distinct approaches to limiting user bias when selecting parameter values and evaluating the relative weights among astrometric parameters. EnLink adopts a locally adaptive distance metric and eliminates the need for parameter tuning through automation. The original SNN relies only on human input for parameter tuning so we modified SNN to run in two stages. We first ran the original SNN 7000 times, each with a randomly generated sample according to within-source co-variance matrices provided in Gaia DR2 and random parameter values within reasonable ranges. During the second stage, we modified SNN to identify the most repeating stellar groups from the 25 798 we obtained in the first stage. We recovered 22 spatially and kinematically coherent groups in the Orion complex, 12 of which were previously unknown. The groups show a wide distribution of distances extending as far as about 150 pc in front of the star-forming Orion molecular clouds, to about 50 pc beyond them, where we, unexpectedly, find several groups. Our results reveal the wealth of sub-structure in the OB association, within and beyond the classical Blaauw Orion OBI sub-groups. A full characterization of the new groups is essential as it offers the potential to unveil how star formation proceeds globally in large complexes such as Orion.
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| 10. |
- Chevance, Mélanie, et al.
(author)
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The Molecular Cloud Lifecycle
- 2020
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In: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 216:4
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Research review (peer-reviewed)abstract
- Giant molecular clouds (GMCs) and their stellar offspring are the building blocks of galaxies. The physical characteristics of GMCs and their evolution are tightly connected to galaxy evolution. The macroscopic properties of the interstellar medium propagate into the properties of GMCs condensing out of it, with correlations between e.g. the galactic and GMC scale gas pressures, surface densities and volume densities. That way, the galactic environment sets the initial conditions for star formation within GMCs. After the onset of massive star formation, stellar feedback from e.g. photoionisation, stellar winds, and supernovae eventually contributes to dispersing the parent cloud, depositing energy, momentum and metals into the surrounding medium, thereby changing the properties of galaxies. This cycling of matter between gas and stars, governed by star formation and feedback, is therefore a major driver of galaxy evolution. Much of the recent debate has focused on the durations of the various evolutionary phases that constitute this cycle in galaxies, and what these can teach us about the physical mechanisms driving the cycle. We review results from observational, theoretical, and numerical work to build a dynamical picture of the evolutionary lifecycle of GMC evolution, star formation, and feedback in galaxies.
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