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Träfflista för sökning "WFRF:(Andersson Johanna 1974) srt2:(2002-2004)"

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1.	Andersson, Johanna, 1974, et al. (author) The complexity of KIT gene mutations and chromosomal rearrangements and their clinical correlations in gastrointestinal stromal (pacemaker cell) tumors 2002 In: American Journal of Pathology. - 0002-9440 .- 1525-2191. ; 160:1, s. 15-22 Journal article (peer-reviewed)
2.	Bümming, Per, 1965, et al. (author) Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17 patients. 2003 In: British journal of cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 89:3, s. 460-4 Journal article (peer-reviewed)abstract Malignant gastrointestinal stromal tumours (GIST) have a poor prognosis. Since these tumours are resistant to conventional radiation and chemotherapy, surgery has been the mainstay of treatment. However, surgery is usually inadequate for the treatment of malignant GIST. Imatinib, a KIT tyrosine kinase inhibitor, has recently been found to have a dramatic antitumour effect on GIST. In this centre-based study of 17 consecutive patients with high-risk or overtly malignant GIST, imatinib was used in three different settings - palliatively, adjuvantly, and neoadjuvantly. The treatment was found to be safe and particularly effective in tumours with activating mutations of exon 11 of the KIT gene. Clinical response to imatinib treatment correlated morphologically to tumour necrosis, hyalinisation, and reduced proliferative activity. The value of neoadjuvant imatinib treatment was illustrated in one case.
3.	Nilsson, Bengt E, 1949, et al. (author) [GIST--a significantly more common tumor than earlier apprehended. New discoveries on the pathogenesis of GIST yielded new medical treatment] 2003 In: Läkartidningen. - 0023-7205. ; 100:11 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Kindblom, Lars-Gunna ... (3); Andersson, Johanna, ... (3); Meis-Kindblom, Jeann ... (3); Ahlman, Håkan, 1947 (2); Nilsson, Bengt E, 19 ... (2); Stierner, Ulrika, 19 ... (2); show more...; Bümming, Per, 1965 (2); Engström, Katarina, ... (2); Jansson, Svante, 194 ... (1); Wängberg, Bo, 1953 (1); Stenman, Göran, 1953 (1); Sjögren, Helene, 196 ... (1); Åman, Pierre, 1953 (1); Klingenstierna, Hans (1); show less...

University: University of Gothenburg (3)

Language: English (2); Swedish (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

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