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7:e Nordiska Forskarsymposiet i Turism 1998
- 1999
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Editorial collection (other academic/artistic)abstract
- Nordiska Forskarsymposiet i Turism genomförs årligen. ETOUR stod som värd för 1998 års symposium som hölls i Åre i början av december. ETOUR har sammanställt konferensrapporten som innehåller de uppsatser som presenterades under symposiet. Deltagande forskare representerar olika perspektiv av turism, vilket gör att rapporten ger en bred översikt över nordisk turismforskning. Uppsatserna behandlar bland annat attraktioner, evenemang, destinationsutveckling, framtidens resande och attityder gentemot turism. Läsaren får en aktuell belysning av turistiska fenomen i denna rapport.
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- Andersson, Tommy D, et al.
(author)
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Leisure events and regional economic impact
- 1999
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Reports (other academic/artistic)abstract
- I dag är det alltid en tuff tävlan om att få arrangera ett stort idrottsevenmang. Regioner och städer är villiga att spendera stora pengar för att utses som arrangör för ett OS, VM och andra mega-event. Den här rapporten tar upp flera aspekter till vad ett stort arrangemang kostar och vad det ger för effekter för respektive region. De stora inkomstkällorna för ett stort arrangemang kan delas in fyra delar: - besökarnas konsumtion. - sponsorpengar. - bidrag från olika myndigheter. - inkomster från medias aktiviteter/rättigheter. I den här rapporten redogörs för utfallet av VM-tävlingarna på skidor i Trondheim 1997.
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- Andersson, Tommy D
(author)
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Local residents attitudes towards a big sports event : an analysis of the World championships in Nordic ski in Norway 1997
- 1999
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Reports (other academic/artistic)abstract
- Allmänhetens åsikter spelar ofta en viktig roll i anbudförfarandet och planeringen inför ett stort evenemang. Syftet med den här studien är att förstå hur lokalbefolkningens åsikter formas. En modell föreslås som bygger på tidigare forskning om stora evenemang (Ritchie, Lyons 1990) och studerar faktorer som bestämmer åskådarnas beslut att besöka ett sport evenemang (Zhang et al, 1995). Modellen testas mot data från 408 intervjuer med lokalbefolkning i Trondheim där 1997 års World Championship in Nordic Ski var förlagt. Resultaten visar att argument som är relaterade till attraktionen av evenemanget, ekonomiska effekter och image effekter alla kan förklara attityderna till evenemanget. Ekonomiska argument är viktigast. Sportintresse och kön verkar ha påverkan på hur mottaglig en person är för olika argument.
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- Andersson, Tommy D
(author)
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Self actualisation in the Antarctic
- 1999
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Reports (other academic/artistic)abstract
- By Surveying 79 travellers in two charter tours to the Antarctic in terms of Need Satisfaction and travel experience, the objective of this study is to look inte two issues: - Is it possible to explain tourists satisfaction by the needs articulated in the Travel Career Ladder? - Will the importance of specific needs shift as predicted by the Travel Career Ladder when tourists get more experienced?
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- Björkegren Sjögren, Camilla
(author)
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Profilin in cell motility and signal transduction studies using site-specific mutagenesis
- 1997
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Doctoral thesis (other academic/artistic)abstract
- When a cell is stimulated by signalling molecules such as growth factors, one immediate response is an increased motile activity of the cell. Membrane lamella and spikes appear at the cell surface and perform undulating movements. This is caused by the activation and reorganisation of the highly dynamic microfilament system, present beneath the cell membrane. The major component of the microfilament system is actin, a protein that can polymerise into filaments -microfilaments-, and several actin-binding proteins which act in concert to organise actin into different supramolecular arrangements. To understand how a signal is transmitted form the exterior of the cell to the microfilament system, it is important to reveal how the activities of different actin-binding proteins are regulated.This thesis focus on the actin-binding protein profilin, which binds actin monomers and regulates actin polymerisation. Profilin also interacts with polyphosphoinositides, which are important signalling molecules, and this association appears to regulate both the function of profilin and the turnover of polyphosphoinositides. Furthermore, profilin binds poly(L-proline) and proline-rich proteins. The latter interaction seems to be involved in the positioning of profilin within a cell, and may also be important for signal transduction-related processes. In the current investigation site-directed mutagenesis was combined with biochemical methods to further investigate the function of profilin.The replacement of two amino acid residues located in a hydrophobic patch on the surface of the profilin molecule was shown to abolish the interaction with poly(L-proline), and enabled the localisation of the poly(L-proline) binding-site to this part of profilin. A new purification method was developed for these profilin mutants and further biochemical characterisation showed that the two mutations also decreased the affinity of profilin for actin. As the poly(L-proline)-binding site is separated from the actin-binding surface of profilin this showed that these amino acid replacements in the poly(L-proline)-binding site also introduced long-range alterations in the profilin molecule.Profilin was shown to be phosphorylated on a serine and a tyrosine residue by an epidermal growth factor receptor complex isolated from stimulated cells. The phosphorylated residues were located to the poly(L-proline) binding site of profilin, and the phosphorylation interfered with the binding of profilin to poly(L-proline). This suggests that this phosphorylation regulate interactions between profilin and proline-rich proteins.The simultaneous deletion of two amino acid residues adjacent to the actin-binding site of profilin was shown to reduce the affinity of profilin for actin, without affecting the interaction of profilin with other ligands. The effect of this mutant profilin on the organisation of the microfilament system in living cells was compared to that of wild type profilin in microinjection experiments. While wild type profilin caused disruption of actin bundles within the cell, the profilin mutant had no apparent effect, showing that the derangement of the actin bundles by profilin is dependent on the stability of the profilin:actin complex.
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