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Search: WFRF:(Boccia L) > (2018)

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1.
  • Di Vita, A, et al. (author)
  • Cerebellar grey matter modifications in lower limb amputees not using prosthesis
  • 2018
  • In: Scientific reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 8:1, s. 370-
  • Journal article (peer-reviewed)abstract
    • Plastic brain changes following peripheral deafferentation, in particular those following limb amputations, are well-documented, with significant reduction of grey matter (GM) in the sensory-motor cerebral areas representing the amputated limb. However, few studies have investigated the role played by the use of a prosthesis in these structural brain modifications. Here we hypothesized that using a functional prosthesis that allows individuals to perform actions may reduce grey matter reduction. We investigated the brain structural reorganization following lower limb amputation by using a Voxel Based Morphometry (VBM) analysis of structural magnetic resonance imaging (MRI) in 8 right-handed individuals with lower limb amputation (LLA) fitted with prostheses (LLAwp), compared to 6 LLA who had never used a prosthesis (LLAnp). 14 age-matched healthy controls were also enrolled (HC). We did not find any significant effect when comparing LLAwp and HC. However we found a decreased GM volume in the bilateral cerebellum in LLAnp compared with HC. These results suggest that prosthesis use prevents GM decrease in the cerebellum after lower limb amputation.
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2.
  • Rota, M, et al. (author)
  • Erratum
  • 2018
  • In: International journal of cancer. - : Wiley. - 1097-0215 .- 0020-7136. ; 143:8, s. E10-E10
  • Journal article (peer-reviewed)
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