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Träfflista för sökning "WFRF:(Daub CO) srt2:(2010-2014)"

Search: WFRF:(Daub CO) > (2010-2014)

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1.	Andersson, R, et al. (author) An atlas of active enhancers across human cell types and tissues 2014 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 507:7493, s. 455- Journal article (peer-reviewed)
2.	Forrest, ARR, et al. (author) A promoter-level mammalian expression atlas 2014 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 507:7493, s. 462- Journal article (peer-reviewed)
3.	Gao, H, et al. (author) Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue 2014 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 19:6, s. 981-992 Journal article (peer-reviewed)
4.	Kulyte, A, et al. (author) Additive effects of microRNAs and transcription factors on CCL2 production in human white adipose tissue 2014 In: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 63:4, s. 1248-1258 Journal article (peer-reviewed)abstract Adipose tissue inflammation is present in insulin-resistant conditions. We recently proposed a network of microRNAs (miRNAs) and transcription factors (TFs) regulating the production of the proinflammatory chemokine (C-C motif) ligand-2 (CCL2) in adipose tissue. We presently extended and further validated this network and investigated if the circuits controlling CCL2 can interact in human adipocytes and macrophages. The updated subnetwork predicted that miR-126/-193b/-92a control CCL2 production by several TFs, including v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), MYC-associated factor X (MAX), and specificity protein 12 (SP1). This was confirmed in human adipocytes by the observation that gene silencing of ETS1, MAX, or SP1 attenuated CCL2 production. Combined gene silencing of ETS1 and MAX resulted in an additive reduction in CCL2 production. Moreover, overexpression of miR-126/-193b/-92a in different pairwise combinations reduced CCL2 secretion more efficiently than either miRNA alone. However, although effects on CCL2 secretion by co-overexpression of miR-92a/-193b and miR-92a/-126 were additive in adipocytes, the combination of miR-126/-193b was primarily additive in macrophages. Signals for miR-92a and -193b converged on the nuclear factor-κB pathway. In conclusion, TF and miRNA-mediated regulation of CCL2 production is additive and partly relayed by cell-specific networks in human adipose tissue that may be important for the development of insulin resistance/type 2 diabetes.
5.	Pardo, LM, et al. (author) Regional differences in gene expression and promoter usage in aged human brains 2013 In: Neurobiology of aging. - : Elsevier BV. - 1558-1497 .- 0197-4580. ; 34:7, s. 1825-1836 Journal article (peer-reviewed)
6.	Plessy, C, et al. (author) Linking promoters to functional transcripts in small samples with nanoCAGE and CAGEscan 2010 In: Nature methods. - : Springer Science and Business Media LLC. - 1548-7105 .- 1548-7091. ; 7:7, s. 528-U67 Journal article (peer-reviewed)
7.	Ramilowski, JA, et al. (author) Glycyrrhiza uralensis transcriptome landscape and study of phytochemicals 2013 In: Plant & cell physiology. - : Oxford University Press (OUP). - 1471-9053 .- 0032-0781. ; 54:5, s. 697-710 Journal article (peer-reviewed)
8.	Ravasi, T, et al. (author) An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man (vol 140, pg 744, 2010) 2010 In: CELL. - : Elsevier BV. - 0092-8674. ; 141:2, s. 369-369 Journal article (other academic/artistic)
9.	Tammimies, K, et al. (author) The molecular network of the dyslexia candidate gene DYX1C1 shows connection to neuronal migration genes and cytoskeletal proteins 2012 In: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. - : Wiley. - 0736-5748 .- 1873-474X. ; 30:8, s. 675-676 Conference paper (other academic/artistic)
10.	Vitezic, M, et al. (author) Building promoter aware transcriptional regulatory networks using siRNA perturbation and deepCAGE 2010 In: Nucleic acids research. - : Oxford University Press (OUP). - 1362-4962 .- 0305-1048. ; 38:22, s. 8141- Journal article (peer-reviewed)

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Result 1-10 of 10

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Type of publication: journal article (9); conference paper (1)

Type of content: peer-reviewed (8); other academic/artistic (2)

Author/Editor: Daub, CO (10); Carninci, P (6); Vitezic, M (5); Lassmann, T (5); Hayashizaki, Y (5); Kawai, J (5); show more...; Suzuki, H. (4); Arner, E (4); Forrest, ARR (4); Bertin, N (4); Arner, P (3); Kawaji, H (3); Heutink, P (3); Hume, DA (3); Mejhert, N (3); Chen, Y. (2); Takahashi, H. (2); Suzuki, M. (2); Lennartsson, A (2); Katayama, S (2); Kere, J (2); Li, K. (2); Itoh, M. (2); Ryden, M (2); Andersson, R. (2); Kondo, N (2); Severin, J (2); Ramilowski, JA (2); Gao, H. (2); Lenhard, B (2); Cannistraci, CV (2); Ravasi, T (2); Stromblad, S (2); Hoof, I (2); Schmidl, C (2); Valen, E (2); Lilje, B (2); Jorgensen, M (2); Burroughs, AM (2); Baillie, JK (2); Ishizu, Y (2); Mungall, CJ (2); Meehan, TF (2); Rehli, M (2); Sandelin, A (2); Hashimoto, T (2); Lorente-Cebrian, S (2); Bajic, VB (2); van Nimwegen, E (2); Medvedeva, YA (2); show less...

University: Karolinska Institutet (10)

Language: English (10)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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