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Enumeration	Reference	Cover	Find
1.	Klionsky, Daniel J, et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). 2016 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 12:1, s. 1-222 Journal article (peer-reviewed)
2.	Dooley, James, et al. (author) Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes 2016 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 48, s. 519-527 Journal article (peer-reviewed)abstract Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic links have remained elusive. T1D results from autoimmune destruction of pancreatic beta cells, whereas beta cell failure in T2D is delayed and progressive. Here we find a new genetic component of diabetes susceptibility in T1D non-obese diabetic (NOD) mice, identifying immune-independent beta cell fragility. Genetic variation in Xrcc4 and Glis3 alters the response of NOD beta cells to unfolded protein stress, enhancing the apoptotic and senescent fates. The same transcriptional relationships were observed in human islets, demonstrating the role of beta cell fragility in genetic predisposition to diabetes.
3.	Bravo, L, et al. (author) 2021 swepub:Mat__t
4.	Tabiri, S, et al. (author) 2021 swepub:Mat__t

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Author/Editor: Davies, M. (2); Evans, H. (2); Jones, G. (2); King, M. (2); Lopes, L. (2); Losada, M. (2); show more...; Martin, B. (2); Negri, G. (2); Nordberg, M. (2); Qureshi, A. (2); Robson, A. (2); Romano, M. (2); Shaw, K. (2); Ventura, D. (2); Wall, R. (2); Williams, S. (2); Yang, H. (2); Morton, A. (2); Davies, E. (2); Liu, H. (2); Valente, P. (2); Liu, T. (2); Bertoli, G (2); Stewart, G. (2); Martin, J. (2); Alves, R. (2); Aytac, E (2); Campain, N (2); Davies, RJ (2); Hompes, R (2); Lakkis, Z (2); McGrath, JS (2); Maciel, J (2); Rausa, E (2); Rottoli, M (2); Shaikh, (2); Tsarkov, P (2); Brown, A. (2); James, A. (2); Zhang, Y. (2); Cardoso, J. (2); Sharma, S. (2); Silva, M. (2); Martin, S. (2); Diaz, S (2); Jones, M. (2); Manca, G. (2); Moore, R. (2); Russ, J. (2); Shaw, S. (2); show less...

University: Lund University (2); Karolinska Institutet (2); Umeå University (1); Stockholm University (1); Linköping University (1); Swedish University of Agricultural Sciences (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (2); Natural sciences (1)

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