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Träfflista för sökning "WFRF:(Duncan J S) srt2:(2005-2009)"

Search: WFRF:(Duncan J S) > (2005-2009)

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  • Dalby, Matthew J, et al. (author)
  • Nanomechanotransduction and interphase nuclear organization influence on genomic control.
  • 2007
  • In: Journal of Cellular Biochemistry. - : Wiley. - 0730-2312 .- 1097-4644. ; 102:5, s. 1234-44
  • Journal article (peer-reviewed)abstract
    • The ability of cells to alter their genomic regulation in response to mechanical conditioning or through changes in morphology and the organization of the interphase nuclei are key questions in cell biology. Here, two nanotopographies have been used as a model surfaces to change cell morphology in order to investigate spatial genomic changes within the nuclei of fibroblasts. Initially, centromeres for chromosome pairs were labeled and the average distance on different substrates calculated. Further to this, Affymetrix whole genome GeneChips were used to rank genomic changes in response to topography and plot the whereabouts on the chromosomes these changes were occurring. It was seen that as cell spreading was changed, so were the positions along the chromosomes that gene regulations were being observed. We hypothesize that as changes in cell and thus nuclear morphology occur, that this may alter the probability of transcription through opening or closing areas of the chromosomes to transcription factors.
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  • Meikle, Peter, et al. (author)
  • A Spitzer Space Telescope Study of SN 2003gd: Still No Direct Evidence that Core-Collapse Supernovae are Major Dust Factories
  • 2007
  • In: The Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 665:1, s. 608-617
  • Journal article (peer-reviewed)abstract
    • We present a new, detailed analysis of late-time mid-infrared observations of the Type II-P supernova (SN) 2003gd. At about 16 months after the explosion, the mid-IR flux is consistent with emission from 4×10-5 Msolar of newly condensed dust in the ejecta. At 22 months emission from pointlike sources close to the SN position was detected at 8 and 24 μm. By 42 months the 24 μm flux had faded. Considerations of luminosity and source size rule out the ejecta of SN 2003gd as the main origin of the emission at 22 months. A possible alternative explanation for the emission at this later epoch is an IR echo from preexisting circumstellar or interstellar dust. We conclude that, contrary to the claim of Sugerman and coworkers, the mid-IR emission from SN 2003gd does not support the presence of 0.02 Msolar of newly formed dust in the ejecta. There is, as yet, no direct evidence that core-collapse supernovae are major dust factories.
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