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- Kindblom-Rising, Kristina, et al.
(author)
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Nursing staff's communication modes in patient transfer before and after an educational intervention
- 2010
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In: Ergonomics. - : Informa UK Limited. - 0014-0139 .- 1366-5847. ; 53:10, s. 1217-1227
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Journal article (peer-reviewed)abstract
- The objective was to explore and describe nursing staff's body awareness and communication in patient transfers and evaluate any changes made after an educational intervention to promote staff competence in guiding patients to move independently. In total, 63 nursing staff from two hospitals wrote weekly notes before and after the intervention. The topics were: A) reflect on a transfer during the last week that you consider was good and one that was poor; B) reflect on how your body felt during a good and a poor transfer. The notes were analysed with content analysis. The results showed five different communication modes connected with nursing staff's physical and verbal communication. These communication modes changed after 1 year to a more verbal communication, focusing on the patient's mobility. The use of instructions indicated a new or different understanding of patient transfer, which may contribute to a development of nursing staff's competence. Statement of Relevance: The present findings indicate that patient transfer consists of communication. Therefore, verbal and bodily communication can have an integral part of training in patient transfer; furthermore, the educational design of such programmes is important to reach the goal of developing new understanding and enhancing nursing staff's competence in patient transfer.
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| 2. |
- Strenn, Nina, 1984, et al.
(author)
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Associations between NFKB and NFKBIL1 polymorphisms and autistic-like traits in a Swedish population of twins
- 2014
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In: 29th World Congress of the International College of Neuropsychopharmacology (CINP), 22-26 June 2014; Vancouver, Canada.
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Conference paper (other academic/artistic)abstract
- Objectives Autism spectrum disorders are a complex group of neurodevelopmental disorders which are characterized by impairments in social interactions and both verbal and nonverbal communication. The immune system has been suggested to be of importance for the development of neuropsychiatric symptoms; for example, elevated levels of cytokines and the inflammation-related transcription factor nuclear factor kappa-B (NFKB) have been reported in autistic individuals. The aim of this study was to investigate possible associations between single nucleotide polymorphisms (SNPs) in NFKB and NFKB inhibitor-like protein 1 (NFKBIL1) and autistic-like traits in a Swedish population of twins. Methods The subjects in this study (n=12426, 9-12 years old) are from “The Child and Adolescent Twin Study in Sweden” (CATSS). Their parents participated in a telephone interview where the children were assessed by the Autism-Tics, ADHD, and Other Comorbidities Inventory (A-TAC) where autistic-like traits are measured using a continuous scale. DNA was extracted from saliva samples and polymorphisms were genotyped. Statistical analyses were performed in the SAS 9.3 (SAS Institute, Inc., Cary, NC) softwear. Results Four out of the five investigated SNPs (NFKB: rs4648022; NFKBIL1: rs2230365, 2239797 and rs2857605) showed significant associations with the A-TAC total autistic-like traits score. Conclusions To our best knowledge, polymorphisms in the genes encoding NFKB and NFKBIL1 have not been studied previously in relation to autism. These proteins may be involved in neuronal development and our findings support the hypothesis of the immune system being important in the aetiology of neuropsychiatric symptoms.
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| 3. |
- Thompson, Paul M., et al.
(author)
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The ENIGMA Consortium : large-scale collaborative analyses of neuroimaging and genetic data
- 2014
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In: BRAIN IMAGING BEHAV. - : Springer Science and Business Media LLC. - 1931-7557 .- 1931-7565. ; 8:2, s. 153-182
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Journal article (peer-reviewed)abstract
- The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.
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