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Search: WFRF:(Engström Wilhelm) > (2010)

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1.
  • Engström, Wilhelm (author)
  • Effects of Insulin-like Growth Factor Binding Protein 7 on Apoptosis in Human Teratocarcinoma Cells In Vitro
  • 2010
  • In: Anticancer Research. - 0250-7005 .- 1791-7530. ; 30, s. 911-914
  • Journal article (peer-reviewed)abstract
    • Human teratocarcinoma cells (Tera-2) deprived of serum undergo programmed cell death which can be counteracted by simultaneous addition of IGF-II. This protective effect of IGF-II was specific in the sense that addition of IGF-binding protein 7 (IGFBP-7) resulted in an increased apoptotic rate almost comparable to that of the classical IGFBPs. Autoradiographic analysis of incorporated tritiated thymidine indicated that the proportion of S-phase cells was comparable, irrespective of total cell numbers. This further suggests that IGF-II rescues cells from apoptosis and that IGFBP-7 is a specific antagonist.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Engström, Wilhelm (2)
University
Swedish University of Agricultural Sciences (2)
Language
English (2)
Research subject (UKÄ/SCB)
Agricultural Sciences (2)
Natural sciences (1)
Year
2010 (2)Undo refine

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