1. |
|
|
2. |
- Clarke, DL, et al.
(author)
-
Generalized potential of adult neural stem cells
- 2000
-
In: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 288:5471, s. 1660-1663
-
Journal article (peer-reviewed)abstract
- The differentiation potential of stem cells in tissues of the adult has been thought to be limited to cell lineages present in the organ from which they were derived, but there is evidence that some stem cells may have a broader differentiation repertoire. We show here that neural stem cells from the adult mouse brain can contribute to the formation of chimeric chick and mouse embryos and give rise to cells of all germ layers. This demonstrates that an adult neural stem cell has a very broad developmental capacity and may potentially be used to generate a variety of cell types for transplantation in different diseases.
|
|
3. |
|
|
4. |
|
|
5. |
|
|
6. |
- Carlen, M., et al.
(author)
-
Functional integration of adult-born neurons
- 2002
-
In: Current Biology. - 0960-9822 .- 1879-0445. ; 12:7, s. 606-608
-
Journal article (peer-reviewed)abstract
- Over the past decade, it has become clear that neural stem cells in the adult mammalian brain continuously generate new neurons, predominantly in the hippocampus and olfactory bulb [1]. However, the central issue of whether these new neurons participate in functional synaptic circuitry has yet to be resolved. Here, we use virus-based transsynaptic neuronal tracing and c-Fos mapping of odor-induced neuronal activity to demonstrate that neurons generated in the adult functionally integrate into the synaptic circuitry of the brain.
|
|
7. |
|
|
8. |
- Cassidy, R, et al.
(author)
-
Neurobiology. Stem cells on the brain
- 2001
-
In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 412:6848, s. 690-691
-
Journal article (other academic/artistic)
|
|
9. |
|
|
10. |
|
|