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- Edvardsson, Sverker, et al.
(författare)
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A search for H/ACA snoRNAs in yeast using MFE secondary structure prediction
- 2003
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Ingår i: Bioinformatics. - : Oxford University Press (OUP). - 1367-4803 .- 1367-4811. ; 19:7, s. 865-873
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Tidskriftsartikel (refereegranskat)abstract
- We develop an algorithm to screen the yeast genome for novel H/ACA snoRNAs. To achieve this, we introduce some new methods for facilitating the search for noncoding RNAs in genomic sequences which are based on properties of predicted minimum free-energy (MFE) secondary structures. The algorithm has been implemented and can be generalized to enable screening of other eukaryote genomes. We find that use of primary sequence alone is insufficient for identifying novel H/ACA snoRNAs. Only the use of secondary structure filters reduces the number of candidates to a manageable size. From genomic context, we identify three strong H/ACA snoRNA candidates. These together with a further 47 candidates obtained by our analysis are being experimentally screened.
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- Gardner, D. J., et al.
(författare)
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Wood composite protection
- 2003
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Ingår i: <em>Wood Deterioration and Preservation</em>. - : American Chemical Society. - 0841237972 ; , s. 399-419
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Bokkapitel (refereegranskat)abstract
- Wood composites should be protected against microbial and insect attack when used outdoors, especially in construction applications with prolonged exposure to moisture. Preservative systems and treatment processes affect composite properties, especially adhesive/wood bonding and mechanical properties. Several common systems for preservation of composites include, 1) the use of pretreated wood, applicable particularly to some solid lumber laminates; 2) in-process preservative treatments favored for composites made from flakes, particles, and fibers where the preservative treatment is incorporated during the manufacturing process; 3) post-process preservative treatments which are generally favored for wood composites made from lumber and veneer; and 4) the use of recycled treated wood elements in manufacturing or the use of wood species with a high natural resistance against biodegradation. This chapter discusses these four preservative methods and presents a general overview of current research concerning preservation practices and techniques in North America including the effect of preservatives on composite properties, durability issues, and degradation modes.
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- Gardner, P., et al.
(författare)
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Optimal alphabets for an RNA world
- 2003
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Ingår i: The Royal Society Prooceedings: Biological Sciences. ; 270, s. 1177-1182
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Tidskriftsartikel (refereegranskat)
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