| 1. |
- Höglund, Anna, 1970-
(author)
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Vampyrer : En kulturkritisk studie av den västerländska vampyrberättelsen från 1700-talet till 2000-talet
- 2009
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Doctoral thesis (other academic/artistic)abstract
- Vampires haunt our culture. They live amongst us, they live with us, and very likely, they live for us. Considering the never fading popularity of vampires, it is obvious that these beings satisfy some kind of basic human need. Why are vampires so popular? What kinds of specific characteristics do vampires possess that lead to our never-ending fascination with them? These are questions that are answered in this dissertation, which deals with the vampire narrative’s most significant transformations during the period 1700-2000. This study reveals that the vampire is a monster that allows both identification and distance, which makes it into an appropriate character for people to use when they tell stories about themselves and the surrounding world. This is reflected in vampire narratives. The nature of vampires and the material of vampire narratives are not something that has undergone random changes in the course of history. These transformations have their origins in various societal and cultural processes. Through studying the historical and cultural contexts that have produced vampire narratives, one can understand why vampires have been portrayed in different ways at different times and places. Similarly, studying the vampire narrative can also be used to understand the history and culture in which the narrative was created. An examination of the vampire narrative’s history from a cultural criticism perspective reveals a distinct pattern. The vampire narrative has always attracted most attention in times of social and cultural unrest. In all of the varying contexts where vampire characters appear throughout a story, a power game is occurring – a game where the vampire’s character is strategically used to express political opinions and strengthen ideological beliefs. The constant appearance of vampires in such power games is a distinctive feature within the history of vampire narratives, and the societal turbulence leaves its impression on the vampire narrative. These impressions are analyzed and interpreted in this dissertation in order to reveal the power and the strategies of power within the discourse in which the narrative has been produced. In order to describe how the vampire character has functioned and continues to function in what the study calls conflicts of power relations, the term and phenomena power improvisation is used. In the description of the history of the vampire narrative, one can discern two important sub-processes. The first describes how the vampire character and narrative have been fashioned into what they are today. During the period of interest, the vampire is transformed from the un-dead of folklore to an attractive nobleman and further into to a Count Dracula, in order to simultaneously be portrayed as what this study terms a human vampire. The second sub-process explains why the vampire character and narrative have been fashioned into what they are today. It describes the political and ideological beliefs which exist in the society where the vampire form is created and which give birth to different kinds of vampires. If, in the past, the vampire was a monster that was used to portray that which humans are afraid of, today it is a monster with which humans identify. This, claims the author, is due to the fact that the age in which we live is to a great extent imbued with the logic of consumer culture. People in a consumer culture live lives filled with demands which influence their self-image. Feelings of inadequacy and isolation are typical. For people of today, the vampire is an ally that offers an alternative and meets those needs that are neglected in a consumer society.
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| 2. |
- Cristea, Alexander, 1966-
(author)
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Effects of Ageing and Physical Activity on Regulation of Muscle Contraction
- 2008
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Doctoral thesis (other academic/artistic)abstract
- The aims of this study were to investigate the mechanisms underlying (1) the ageing-related motor handicap at the whole muscle, cellular, contractile protein and myonuclear levels; and (2) ageing-related differences in muscle adaptability.In vivo muscles function was studied in the knee extensors. Decreases were observed in isokinetic and isometric torque outputs in old age in the sedentary men and women and elite master sprinters. A 20-week long specific sprint and resistance training successfully improved the maximal isometric force and rate of force development in a subgroup of master sprinters.In vitro measurements were performed in muscle biopsies from the vastus lateralis muscle. Immunocytochemical and contractile measurements in single membrane permeabilized muscle fibres demonstrated ageing- and gender-related changes at the myofibrillar level. In sedentary subjects, data showed a preferential decrease in the size of muscle fibres expressing type IIa MyHC in men, lower force generating capacity in muscle fibres expressing the type I MyHC isoform in both men and women and lower maximum velocity of unloaded shortening (V0) in fibres expressing types I and IIa MyHC isoforms in both men and women. The master sprinters also experienced the typical ageing-related reduction in the size of fast-twitch fibres, a shift toward a slower MyHC isoform profile and a lower V0 of type I MyHC fibres, which played a role in the decline in explosive force production capacity. The fast-twitch fibre area increased after the resistance training period. A model combining single muscle fibre confocal microscopy with a novel algorithm for 3D imaging of myonuclei in single muscle fibre segments was introduced to study the spatial organisation of myonuclei and the size of individual myonuclear domains (MNDs). Significant changes in the MND size variability and myonuclear organization were observed in old age, irrespective gender and fibre type. Those changes may influence the local quantity of specific proteins per muscle fibre volume by decreased and/or local cooperativity of myonuclei in a gender and muscle fibre specific manner.In conclusion, the ageing-related impairments in in vivo muscle function were related to significant changes in morphology, contractile protein expression and regulation at the muscle fibre level. It is suggested that the altered myonuclear organisation observed in old age impacts on muscle fibre protein synthesis and degradation with consequences for the ageing-related changes in skeletal muscle structure and function. However, the improved muscle function in response to a 20-week intense physical training regime in highly motivated physically active old subjects demonstrates that all ageing-related in muscle function are not immutable.
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| 3. |
- Höglund, Carina, 1981-
(author)
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Reactive Magnetron Sputter Deposition and Characterization of Thin Films from the Ti-Al-N and Sc-Al-N Systems
- 2009
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Licentiate thesis (other academic/artistic)abstract
- This Thesis treats the growth and characterization of ternary transition metal nitride thin films. The aim is to probe deeper into the Ti-Al-N system and to explore the novel Sc-Al-N system. Thin films were epitaxially grown by reactive magnetron sputtering from elemental targets onto single-crystal substrates covered with a seed layer. Elastic recoil detection analysis and Rutherford backscattering spectroscopy were used for compositional analysis and depth profiling. Different x-ray diffraction techniques were employed, ex situ using Cu radiation and in situ during deposition using synchrotron radiation, to identify phases, to obtain information about texture, and to determine the thickness and roughness evolution of layers during and after growth. Transmission electron microscopy was used for overview and lattice imaging, and to obtain lattice structure information by electron diffraction. Film properties were determined using van der Pauw measurements of the electrical resistivity, and nanoindentation for the materials hardness and elastic modulus. The epitaxial Mn+1AXn phase Ti2AlN was synthesized by solid-state reaction during interdiffusion between sequentially deposited layers of (0001)-oriented AlN and Ti thin films. When annealing the sample, N and Al diffused into the Ti, forming Ti3AlN at 400 ºC and Ti2AlN at 500 ºC. The Ti2AlN formation temperature is 175 ºC lower than earlier reported results. Ti4AlN3 thin films were, however, not possible to synthesize when depositing films with a Ti:Al:N ratios of 4:1:3. Substrate temperatures at 600 ºC yielded an irregularly stacked Tin+1AlNn layered structure because of the low mobility of Al adatoms. An increased temperature led, however, to an Al deficiency due to an out diffusion of Al atoms, and formation of Ti2AlN phase and Ti1-xAlxN cubic solid solution. In the Sc-Al-N system the first ternary phase was discovered, namely the perovskite Sc3AlN, with a unit cell of 4.40 Å. Its existence was supported by ab initio calculations of the enthalpy showing that Sc3AlN is thermodynamically stable with respect to the binaries. Sc3AlN thin films were experimentally found to have a hardness of 14.2 GPa, an elastic modulus of 21 GPa, and a room temperature resistivity of 41.2 μΩcm.
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| 4. |
- Forsberg, Lars
(author)
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Genetic Aspects of Sexual Selection and Mate Choice in Salmonids
- 2008
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Doctoral thesis (other academic/artistic)abstract
- The long-term genetic consequences of supportive breeding programs are not well understood. Nevertheless, stocking populations with hatchery-produced fish to compensate for losses of natural production are common practice, for example after constructions of hydroelectric power dams. Hatcheries typically fertilize eggs using ‘mixed-milt fertilizations’, without consideration to natural reproductive behaviours, and hence, natural selective regimes would be altered. Here, a series of experiments with focus on Mhc and mate choice in a population of brown trout (Salmo trutta L.) with a history of long-term stocking are presented. The major histocompatibility complex (Mhc) constitutes of genes coding for antigen presentation in the vertebrate immune system. In addition to the immunological function, Mhc genes might also influence reproductive behaviours such as mate choice. For example, in some species individuals are able to recognize Mhc genotypes of potential mates and to some extent base their mate choice on this information. Here, I address these questions on brown trout. Can the phenomena be observed in brown trout? Could such mechanisms help individuals to avoid inbreeding, or are other mechanisms important? How does the artificial rearing of fish for enhancement of natural populations relate to these issues? The results presented here, in combination with previous work, shows that several factors are important in the process of pair formation in salmonid species. For example, females of the studied population used more than a single criterion when choosing among the available mates Mhc genes and males with certain Mhc genotypes achieved more matings, possibly an effect from increased fighting ability. Further, the population appears to contain an unnatural high level of Mhc variation, and some results indicate that the population might suffer from outbreeding depression at the Mhc. These negative effects are most likely derived from compression of sub-populations after dam-construction, in combination with supportive breeding with no consideration to natural spawning behaviour.
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| 5. |
- Höglund, Anders
(author)
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Controllable degradation product migration from biomedical polyester-ethers
- 2007
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Licentiate thesis (other academic/artistic)abstract
- The use of degradable biomedical materials has during the past decades indeed modernized medical science, finding applications in e.g. tissue engineering and drug delivery. The key question is to adapt the material with respect to mechanical properties, surface characteristics and degradation profile to suit the specific application. Degradation products are generally considered non-toxic and they are excreted from the human body. However, large amounts of hydroxy acids may induce a pH decrease and a subsequent inflammatory response at the implantation site. In this study, macromolecular design and a combination of cross-linking and adjusted hydrophilicity are utilized as tools to control and tailor degradation rate and subsequent release of degradation products from biomedical polyester-ethers. A series of different homo- and copolymers of -caprolactone (CL) and 1,5-dioxepan-2-one (DXO) were synthesized and their hydrolytic degradation was monitored in phosphate buffer solution at pH 7.4 and 37 °C for up to 546 days. The various materials comprised linear DXO/CL triblock and multiblock copolymers, PCL linear homopolymer and porous structure, and random cross-linked homo- and copolymers of CL/DXO using 2,2’-bis-(ε-caprolactone-4-yl) propane (BCP) as a cross-linking agent. The results showed that macromolecular engineering and controlled hydrophilicity of cross-linked networks were useful implements for customizing the release rate of acidic degradation products in order to prevent the formation of local acidic environments and thereby reduce the risk of inflammatory responses in the body.
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