| 1. |
- Wu, JM, et al.
(author)
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Blue light induced apoptosis in rat retina
- 1999
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In: Eye (London, England). - : Springer Science and Business Media LLC. - 0950-222X .- 1476-5454. ; 1313 ( Pt 4), s. 577-583
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Journal article (peer-reviewed)
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| 2. |
- Bhatnagar, Amit, et al.
(author)
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Utilization of agro-industrial and municipal waste materials as potential adsorbents for water treatment- A Review
- 2010
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In: Chemical Engineering Journal. - : Elsevier BV. - 1385-8947 .- 1873-3212. ; 157:2-3, s. 277-296
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Journal article (peer-reviewed)abstract
- Adsorption process has been proven one of the best water treatment technologies around the world and activated carbon is undoubtedly considered as universal adsorbent for the removal of diverse types of pollutants from water. However, widespread use of commercial activated carbon is sometimes restricted due to its higher costs. Attempts have been made to develop inexpensive adsorbents utilizing numerous agro-industrial and municipal waste materials. Use of waste materials as low-cost adsorbents is attractive due to their contribution in the reduction of costs for waste disposal, therefore contributing to environmental protection. In this review, an extensive list of low-cost adsorbents (prepared by utilizing different types of waste materials) from vast literature has been compiled and their adsorption capacities for various aquatic pollutants as available in the literature are presented. It is evident from the literature survey that various low-cost adsorbents have shown good potential for the removal of various aquatic pollutants. However, there are few issues and drawbacks on the use of low-cost adsorbents in water treatment that have been discussed in this paper. Additionally, more research is needed to find the practical utility of low-cost adsorbents on commercial scale.
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| 3. |
- Graham, Daniel B., et al.
(author)
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Harmonic waves and sheath rectification in type III solar radio bursts
- 2014
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In: J GEOPHYS RES-SPACE. - 2169-9380. ; 119:2, s. 723-741
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Journal article (peer-reviewed)abstract
- In type III solar radio bursts and planetary foreshocks, Langmuir waves are produced by electron beams and converted partially to radio waves by linear and nonlinear processes. Lower amplitude second harmonic electric fields are observed simultaneously during the most intense Langmuir wave events in type III source regions. The electric fields at the harmonic frequencies can arise from various mechanisms, such as radio wave emission by either coalescence or antenna mechanisms, nonlinear currents, harmonics of Langmuir waves, electron trapping in Langmuir wave potentials, and Langmuir wave rectification at the sheath surrounding the spacecraft, or they can result from instrumental harmonics. In this paper the relative powers and electric field vectors of Langmuir waves and the harmonic fields are compared for multiple events. The structure of the harmonic field is shown to be determined by the Langmuir waveform, but the harmonic field direction is typically closely aligned with the solar wind flow. The magnitude, structure, and orientation of the harmonic fields is used to determine which processes are responsible. It is shown that the dominant process generating the observed harmonic fields is Langmuir wave rectification at the sheath surrounding the spacecraft. Key Points Intense Langmuir waves and harmonic fields are observed simultaneously Harmonic fields are primarily produced by sheath rectification Some evidence for nonlinear currents is found
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| 6. |
- Shrivastava, Nidhi, et al.
(author)
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Important amino acid residues of hexachlorocyclohexane dehydrochlorinases (LinA) for enantioselective transformation of hexachlorocyclohexane isomers
- 2017
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In: Biodegradation. - : SPRINGER. - 0923-9820 .- 1572-9729. ; 28:2-3, s. 171-180
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Journal article (peer-reviewed)abstract
- LinA-type1 and LinA-type2 are two well-characterized variants of the enzyme hexachlorocyclohexane (HCH)-dehydrochlorinase. They differ from each other at ten amino acid positions and exhibit differing enantioselectivity for the transformation of the (-) and (+) enantiomers of alpha-HCH. Amino acids responsible for this enantioselectivity, however, are not known. An in silico docking analysis identified four amino acids (K20, L96, A131, and T133) in LinA-type1 that could be involved in selective binding of the substrates. Experimental studies with constructed mutant enzymes revealed that a combined presence of three amino acid changes in LinA-type1, i.e. K20Q, L96C, and A131G, caused a reversal in its preference from the (-) to the (+) enantiomer of alpha-HCH. This preference was enhanced by the additional amino acid change T133 M. Presence of these four changes also caused the reversal of enantioselectivity of LinA-type1 for delta-HCH, and beta-, gamma-, and delta-pentachlorocyclohexens. Thus, the residues K20, L96, A131, and T133 in LinA-type1 and the residues Q20, C96, G131, and M133 in LinA-type 2 appear to be important determinants for the enantioselectivity of LinA enzymes.
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| 7. |
- Warringer, Jonas, 1973, et al.
(author)
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Chemogenetic fingerprinting by analysis of cellular growth dynamics.
- 2008
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In: BMC chemical biology. - : Springer Science and Business Media LLC. - 1472-6769. ; 8
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Journal article (peer-reviewed)abstract
- ABSTRACT: BACKGROUND: A fundamental goal in chemical biology is the elucidation of on- and off-target effects of drugs and biocides. To this aim chemogenetic screens that quantify drug induced changes in cellular fitness, typically taken as changes in composite growth, is commonly applied. RESULTS: Using the model organism Saccharomyces cerevisiae we here report that resolving cellular growth dynamics into its individual components, growth lag, growth rate and growth efficiency, increases the predictive power of chemogenetic screens. Both in terms of drug-drug and gene-drug interactions did the individual growth variables capture distinct and only partially overlapping aspects of cell physiology. In fact, the impact on cellular growth dynamics represented functionally distinct chemical fingerprints. DISCUSSION: Our findings suggest that the resolution and quantification of all facets of growth increases the informational and interpretational output of chemogenetic screening. Hence, by facilitating a physiologically more complete analysis of gene-drug and drug-drug interactions the here reported results may simplify the assignment of mode-of-action to orphan bioactive compounds.
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