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Träfflista för sökning "WFRF:(Houltz Anders) "

Search: WFRF:(Houltz Anders)

  • Result 1-10 of 86
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2.
  • Andersson, Anders, et al. (author)
  • Interleukin-16-producing NK cells and T-cells in the blood of tobacco smokers with and without COPD
  • 2016
  • In: International Journal of Chronic Obstructive Pulmonary Disease. - : Informa UK Limited. - 1178-2005. ; 11, s. 2245-2258
  • Journal article (peer-reviewed)abstract
    • Background: Long-term exposure to tobacco smoke causes local inflammation in the airways that involves not only innate immune cells, including NK cells, but also adaptive immune cells such as cytotoxic (CD8(+)) and helper (CD4(+)) T-cells. We have previously demonstrated that long-term tobacco smoking increases extracellular concentration of the CD4(+)-recruiting cytokine interleukin (IL)-16 locally in the airways. Here, we hypothesized that tobacco smoking alters IL-16 biology at the systemic level and that this effect involves oxygen free radicals (OFR). Methods: We quantified extracellular IL-16 protein (ELISA) and intracellular IL-16 in NK cells, T-cells, B-cells, and monocytes (flow cytometry) in blood samples from long-term tobacco smokers with and without chronic obstructive pulmonary disease (COPD) and in never-smokers. NK cells from healthy blood donors were stimulated with water-soluble tobacco smoke components (cigarette smoke extract) with or without an OFR scavenger (glutathione) in vitro and followed by quantification of IL-16 protein. Results: The extracellular concentrations of IL-16 protein in blood did not display any substantial differences between groups. Notably, intracellular IL-16 protein was detected in all types of blood leukocytes. All long-term smokers displayed a decrease in this IL-16 among NK cells, irrespective of COPD status. Further, both NK and CD4(+) T-cell concentrations displayed a negative correlation with pack-years. Moreover, cigarette smoke extract caused release of IL-16 protein from NK cells in vitro, and this was not affected by glutathione, in contrast to the decrease in intracellular IL-16, which was prevented by this drug. Conclusion: Long-term exposure to tobacco smoke does not markedly alter extracellular concentrations of IL-16 protein in blood. However, it does decrease the intracellular IL-16 concentrations in blood NK cells, the latter effect involving OFR. Thus, long-term tobacco smoking exerts an impact at the systemic level that involves NK cells; innate immune cells that are critical for host defense against viruses and tumors-conditions that are over-represented among smokers.
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  • Franzén, Anders, et al. (author)
  • Brukandets dynamik
  • 2023
  • In: Bebyggelsehistorisk tidskrift. - Uppsala : Föreningen Bebyggelsehistorisk tidskrift. - 0349-2834 .- 2002-3812. ; 85, s. 5-7
  • Journal article (pop. science, debate, etc.)
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  • Agnidakis, Paul, 1974-, et al. (author)
  • Stadsrummet reflekterar tiden
  • 2016
  • In: Bebyggelsehistorisk tidskrift. - : Föreningen Bebyggelsehistorisk tidskrift. - 0349-2834 .- 2002-3812. ; :71, s. 5-6
  • Journal article (other academic/artistic)
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7.
  • Arbete pågår : - i tankens mönster och kroppens miljöer
  • 2008
  • Editorial collection (other academic/artistic)abstract
    • Work is always in progress, somewhere, in some form. In a historical perspective the view of work has changed, as have the contexts where work takes place. Still there are strongly rooted images of what work is – in the patterns of thought and material conditions.This book embarks from the idea that work is something both immaterial and material. It discusses work as a conception and cultural norm, but also as something very tangible and concrete.Researchers from an array of scientific fields have gathered together around these questions. The idea has been to twist and turn the conceptions of what work is and – embarking from one’s own discipline – to contribute new perspectives to this topic.
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  • Avango, Dag, 1965-, et al. (author)
  • Industriarvet Idag
  • 2013
  • In: Bebyggelsehistorisk tidskrift. - 0349-2834. ; , s. 5-9
  • Journal article (other academic/artistic)abstract
    • Introduction to thematic issue of Bebyggelsehistorisk tidskrift, identifying trends.
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10.
  • Avango, Dag, et al. (author)
  • Industriarvet idag
  • 2013
  • In: Bebyggelsehistorisk tidskrift. - : Föreningen Bebyggelsehistorisk tidskrift. - 0349-2834 .- 2002-3812. ; :65, s. 5-9
  • Journal article (other academic/artistic)
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  • Result 1-10 of 86
Type of publication
journal article (27)
conference paper (23)
book chapter (17)
editorial collection (6)
review (5)
book (2)
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other publication (2)
reports (1)
doctoral thesis (1)
research review (1)
licentiate thesis (1)
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Type of content
other academic/artistic (44)
peer-reviewed (30)
pop. science, debate, etc. (12)
Author/Editor
Houltz, Anders, 1966 ... (45)
Houltz, Anders (33)
Houltz, Erik, 1951 (5)
Avango, Dag, 1965- (5)
Avango, Dag (4)
Fors, Hjalmar (3)
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Houltz, Birgitta, 19 ... (3)
Peix Geldart, Benito (3)
Baraldi, Enrico (3)
Snickars, Pelle, 197 ... (2)
af Geijerstam, Jan (2)
Agnidakis, Paul, 197 ... (2)
Godhe, Michael, 1964 ... (2)
Gustafsson, Per M., ... (2)
Silvén, Eva (2)
Martinsson, Andreas (2)
Lindgren, Sophie, 19 ... (2)
Källström, Magnus (2)
Nisser, Marie (2)
Lindblad, Anders, 19 ... (2)
Ricksten, Sven-Erik, ... (2)
Franzén, Anders (2)
Magnusson, Lars (1)
Magnusson, Jesper (1)
Andersson, Anders (1)
Morell, Mats, 1955- (1)
Löfgren, Eva, 1971 (1)
Stenqvist, Ola, 1944 (1)
Jeppsson, Anders, 19 ... (1)
Qvarfordt, Ingemar, ... (1)
Sörlin, Sverker (1)
Alm, Göran (1)
Johansson, Björn Axe ... (1)
Stendahl, Jenny (1)
Lindén, Anders, 1961 (1)
Tengvall, Sara, 1977 (1)
Sörlin, Sverker, 195 ... (1)
Bossios, Apostolos, ... (1)
Malmhäll, Carina, 19 ... (1)
Sjöstrand, Margareta ... (1)
Svensson, Tony (1)
Isacson, Maths (1)
Lundström, Brita (1)
Morell, Mats (1)
Hyllner, Monica, 196 ... (1)
Gilljam, Marita, 195 ... (1)
Bäckersten, Elin (1)
Gullström, Charlie (1)
Sjöholm, Jennie, 197 ... (1)
Holm, Olof (1)
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University
Royal Institute of Technology (53)
Uppsala University (17)
University of Gothenburg (11)
Umeå University (4)
Lund University (3)
Linköping University (2)
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University College of Arts, Crafts and Design (2)
Södertörn University (2)
Swedish National Heritage Board (2)
Luleå University of Technology (1)
Stockholm University (1)
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Language
Swedish (49)
English (37)
Research subject (UKÄ/SCB)
Humanities (69)
Social Sciences (8)
Medical and Health Sciences (6)
Engineering and Technology (2)
Agricultural Sciences (1)

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