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- Bengtsson, Daniel, et al.
(author)
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Zipper performance when mixing ADSL and VDSL in terms of reach and capacity
- 1997
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Reports (other academic/artistic)abstract
- In this contribution we have examined how the maximum reach vary at different bit rates on a VDSL system, when different numbers of ADSL and VDSL systems share the same binder. In this context it is concluded that when using the Zipper duplex scheme, VDSL can coexist with ADSL in the same binder without a significant degradation in reach. Further, it is shown that the Zipper duplex scheme secure that ADSL is not disturbed by NEXT from VDSL The Zipper performance has also been compared with both a TDD proposal and a FDD proposal. The results from this comparison shows that Zipper outperforms FDD and TDD in terms of extended reach at all studied mixes of ADSL and VDSL sharing the same binder. For example with a moderate number (5) of ADSL disturbers, the Zipper reach is 150 meters longer than for TDD, and is 350 meters longer than for FDD when studying the medium range asymmetrical bit rate (26:3.2 Mbps).
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2. |
- Börjesson, Per Ola, et al.
(author)
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A low-complexity PAR-reduction method for DMT-VDSL
- 1999
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In: Proceedings of the 5th International Symposium on Digital Signal Processing for Communication Systems. ; , s. 164-169
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Conference paper (peer-reviewed)abstract
- DMT-VDSL signals have a high peak-to-average power ratio (PAR). In the transmitters, the PAR governs the necessary resolution of the digital-to-analog converter (DAC) and is an important factor for the power consumption of the line-driver. Aiming at implementation in a specific system, we propose a low complexity PAR-reduction method based on the iterative algorithm derived in [5, 20, 24, 25]. We maintain good performance while stressing a straigthforward and low-complex implementation. Key elements of the method are: low latency; no loss in data rate; precalculated and stored peak-cancellation waveform; and bit-shifts (multiplication with powers of two) replacing the scaling of the waveform. Computer simulations show that, for a DMT frame length of 4096 samples and a frame clip rate of 10-4, the PAR can be reduced about 1.5 to 2.0 dB, depending on the number of peaks cancelled. When multiplication is replaced by bit-shifts, the reduction is still 1.5-1.7 dB.
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4. |
- Garkavij, Michael, et al.
(author)
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Extracorporeal immunoadsorption from whole blood based on the avidin-biotin concept. Evaluation of a new method
- 1996
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In: Acta Oncologica. - : Informa UK Limited. - 1651-226X .- 0284-186X. ; 35:3, s. 309-312
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Journal article (peer-reviewed)abstract
- This study of 36 rats with rat colon adenocarcinoma transplants was carried out to investigate the efficacy of a new method of whole blood immunoadsorption (WBIA) in removing biotinylated monoclonal antibodies (MAbs) directly from unseparated blood, in order to increase 'the tumor/normal-tissue uptake ratio', as compared with extracorporeal immunoadsorption (ECIA) of antibodies from plasma. Compared with the ECIA system, the overall volume of the WBIA system (comprising only a pump, an adsorption column, a drop-chamber and tubings) was less (3.6 vs. 6.2 ml), and procedure duration 2 h less. The 17 rats undergoing the WBIA procedure, started 12 h after i.v. injection of 4.0-4.5 MBq 125I-BR96-biotin, manifested neither hemolysis nor any other complication; no signs of organ edema were found at dissection; whole body and blood radioactivity values were reduced by 51% and 89.5%, respectively. The WBIA method was as effective as ECIA, but technically simpler, safer and more reliable.
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5. |
- Garkavij, Martin, et al.
(author)
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Extracorporeal whole-blood immunoadsorption enhances radioimmunotargeting of iodine-125-labeled BR96-biotin monoclonal antibody
- 1997
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In: Journal of Nuclear Medicine. - 0161-5505. ; 38:6, s. 895-901
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Journal article (peer-reviewed)abstract
- This study investigates the efficacy of tumor radioimmunotargeting with 125I-labeled BR96-biotin monoclonal antibody using a new method, whole-blood immunoadsorption (WBIA), based on direct adsorption of unbound monoclonal antibody (MAb) from blood without preceding separation of plasma. METHODS: Highly tumor-reactive, internalizing, chimeric BR96 MAb of isotype IgG1 binds to a tumor-associated Lewis-type (Le(Y)) cell surface antigen. Forty-six Brown Norwegian male rats were inoculated intramuscularly and beneath the liver or kidney capsule with syngeneic rat colon carcinoma BN7005, expressing Lewis-type antigen, and investigated. The rats were injected intravenously with 3.5-4.5 MBq 125I-labeled BR96-biotin. Twenty of the rats underwent WBIA starting 5 or 12 hr after injection. About six blood volumes were passed through an avidin-gel adsorption column during 2 hr. RESULTS: By using WBIA, whole-body radioactivity was reduced by 50%, and plasma activity by 85%. Both directly after completion of WBIA and 33 hr later, the activity uptake in tumors manifested only a nonsignificant decrease as compared with corresponding controls (p > 0.05) and had approximately similar time-activity curves. Uptake ratios for tumor (T):bone marrow, T:liver, T:kidney and T:lung were enhanced 2.3- to 3.5-fold in all three tumor models, as compared with controls. The ratio of liver tumor to bone marrow was improved from 10:1 to 30:1. CONCLUSION: This new method of WBIA yields significantly improved radioimmunotargeting of highly tumor-reactive, internalizing MAb BR96.
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6. |
- Isaksson, Mikael, et al.
(author)
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Zipper : a duplex scheme for VDSL based on DMT
- 1997
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Reports (other academic/artistic)abstract
- A duplex scheme for DMT-based VDSL systems is presented here. It offers a solution to the problem with NEXT and near-echoes in broadband communications. The scheme has high duplex efficiency, low latency, and attractive transmit power features. However, hardware verification remains.
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7. |
- Monstein, Hans-Jurg, et al.
(author)
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Division of the genus Enterococcus into species groups using PCR-based molecular typing methods
- 1998
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In: Microbiology. - : Microbiology Society. - 1350-0872 .- 1465-2080. ; 144:5, s. 1171-1179
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Journal article (peer-reviewed)abstract
- Broad-range 16S rDNA PCR (BR-PCR) applied to DNA from 32 clinical enterococcal isolates and 12 other enterococci from a clinical reference collection followed by species-specific hybridization analysis identified 25 strains of Enterococcus faecalis and 19 Enterococcus species. Randomly amplified polymorphic DNA (RAPD) analysis using UPGMA clustering on the same material revealed four different clusters at a similarity level of 49%. Based on partial 16S rDNA sequence analysis of variable regions V4 and V9, it was possible to divide the 19 type strains specifying the genus Enterococcus into 12 different 16S rDNA species groups. The type strain distribution then served as a template for the analysis of the other 44 strains which were assigned to four different species groups (a-d) based on their 16S rDNA motifs. There was good agreement with the RAPD clusters. Species group a was an individual species line containing 25 strains that were identified as E. faecalis. Group b also represented an individual species line of 12 strains identified as E. faecium. The remaining seven strains that formed species groups c and d could not be fully identified to species by this analysis. It was concluded that BR-PCR of 16S rDNA followed by partial sequence analysis of the PCR products is a reliable technique for the identification and classification of enterococci. Further division of unresolved species groups should be achievable if regions other than V4 and V9 of 16S rDNA are also analysed
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