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Träfflista för sökning "WFRF:(Jansen Anna C.) srt2:(2018)"

Search: WFRF:(Jansen Anna C.) > (2018)

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  • Evangelou, Evangelos, et al. (author)
  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
  • 2018
  • In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 50:10, s. 1412-1425
  • Journal article (peer-reviewed)abstract
    • High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.
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2.
  • Zamora, Juan Carlos, et al. (author)
  • Considerations and consequences of allowing DNA sequence data as types of fungal taxa
  • 2018
  • In: IMA Fungus. - : INT MYCOLOGICAL ASSOC. - 2210-6340 .- 2210-6359. ; 9:1, s. 167-185
  • Journal article (peer-reviewed)abstract
    • Nomenclatural type definitions are one of the most important concepts in biological nomenclature. Being physical objects that can be re-studied by other researchers, types permanently link taxonomy (an artificial agreement to classify biological diversity) with nomenclature (an artificial agreement to name biological diversity). Two proposals to amend the International Code of Nomenclature for algae, fungi, and plants (ICN), allowing DNA sequences alone (of any region and extent) to serve as types of taxon names for voucherless fungi (mainly putative taxa from environmental DNA sequences), have been submitted to be voted on at the 11th International Mycological Congress (Puerto Rico, July 2018). We consider various genetic processes affecting the distribution of alleles among taxa and find that alleles may not consistently and uniquely represent the species within which they are contained. Should the proposals be accepted, the meaning of nomenclatural types would change in a fundamental way from physical objects as sources of data to the data themselves. Such changes are conducive to irreproducible science, the potential typification on artefactual data, and massive creation of names with low information content, ultimately causing nomenclatural instability and unnecessary work for future researchers that would stall future explorations of fungal diversity. We conclude that the acceptance of DNA sequences alone as types of names of taxa, under the terms used in the current proposals, is unnecessary and would not solve the problem of naming putative taxa known only from DNA sequences in a scientifically defensible way. As an alternative, we highlight the use of formulas for naming putative taxa (candidate taxa) that do not require any modification of the ICN.
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Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Gyllensten, Ulf B. (1)
Larsson, Ellen, 1961 (1)
Svantesson, Sten (1)
Kõljalg, Urmas (1)
Saar, Irja (1)
Ghobad-Nejhad, Masoo ... (1)
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Pawlowska, Julia (1)
Suija, Ave (1)
Peintner, Ursula (1)
Khaw, Kay-Tee (1)
Salomaa, Veikko (1)
Jula, Antti (1)
Perola, Markus (1)
Lind, Lars (1)
Borovicka, Jan (1)
Raitakari, Olli T (1)
Melander, Olle (1)
Svensson, Måns (1)
Campbell, Harry (1)
Rudan, Igor (1)
Strachan, David P (1)
Sundström, Johan, Pr ... (1)
Evangelou, Marina (1)
Dimou, Niki (1)
Nagy, István (1)
Wareham, Nicholas J. (1)
Tibell, Leif (1)
Johansson, Åsa (1)
Almgren, Peter (1)
Laakso, Markku (1)
Ridker, Paul M. (1)
Chasman, Daniel I. (1)
Amin, Najaf (1)
van Duijn, Cornelia ... (1)
Rose, Lynda M (1)
Langenberg, Claudia (1)
Paré, Guillaume (1)
Boehnke, Michael (1)
Hamsten, Anders (1)
Scott, Robert A (1)
Shah, Nabi (1)
Gaziano, J Michael (1)
Havulinna, Aki S. (1)
Ripatti, Samuli (1)
Kähönen, Mika (1)
Lehtimäki, Terho (1)
Thor, Göran (1)
Enroth, Stefan, 1976 ... (1)
Ahti, Teuvo (1)
Mayrhofer, Helmut (1)
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University
Uppsala University (2)
Lund University (2)
University of Gothenburg (1)
Stockholm University (1)
Karolinska Institutet (1)
Swedish Museum of Natural History (1)
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Swedish University of Agricultural Sciences (1)
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Language
English (2)
Research subject (UKÄ/SCB)
Natural sciences (2)
Medical and Health Sciences (1)
Year
2018 (2)Undo refine

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