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Träfflista för sökning "WFRF:(Joshi PK) srt2:(2021)"

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Enumeration	Reference	Cover	Find
1.	2021 swepub:Mat__t
2.	Chen, J, et al. (author) The trans-ancestral genomic architecture of glycemic traits 2021 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 53:6, s. 840- Journal article (peer-reviewed)
3.	Graham, SE, et al. (author) The power of genetic diversity in genome-wide association studies of lipids 2021 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 600:7890, s. 675- Journal article (peer-reviewed)
4.	Ning, Z, et al. (author) Nontrivial Replication of Loci Detected by Multi-Trait Methods 2021 In: Frontiers in genetics. - : Frontiers Media SA. - 1664-8021. ; 12, s. 627989- Journal article (peer-reviewed)abstract The ever-growing genome-wide association studies (GWAS) have revealed widespread pleiotropy. To exploit this, various methods that jointly consider associations of a genetic variant with multiple traits have been developed. Most efforts have been made concerning improving GWAS discovery power. However, how to replicate these discovered pleiotropic loci has yet to be discussed thoroughly. Unlike a single-trait scenario, multi-trait replication is not trivial considering the underlying genotype-multi-phenotype map of the associations. Here, we evaluate four methods for replicating multi-trait associations, corresponding to four levels of replication strength. Weak replication cannot justify pleiotropic genetic effects, whereas strong replication using our developed correlation methods can inform consistent pleiotropic genetic effects across the discovery and replication samples. We provide a protocol for replicating multi-trait genetic associations in practice. The described methods are implemented in the free and open-source R package MultiABEL.
5.	Ruth, KS, et al. (author) Genetic insights into biological mechanisms governing human ovarian ageing 2021 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 596:7872, s. 393-397 Journal article (peer-reviewed)
6.	Schache, AG, et al. (author) Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery 2021 In: BJS open. - : Oxford University Press (OUP). - 2474-9842. ; 5:6 Journal article (peer-reviewed)
7.	Zhou, Bin, et al. (author) Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants 2021 In: Lancet (London, England). - : Elsevier. - 1474-547X .- 0140-6736. ; 398:10304, s. 957-980 Journal article (peer-reviewed)

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Type of publication: journal article (6)

Type of content: peer-reviewed (6)

Author/Editor: Peters, A (4); Gudnason, V (4); Ikram, MA (4); Campbell, A (4); Wilson, JF (4); Polašek, O. (4); show more...; Joshi, PK (4); Liu, J. (3); Hottenga, JJ (3); Willemsen, G (3); Mahajan, A. (3); Jonas, JB (3); Langenberg, C. (3); Boomsma, DI (3); Chen, ZM (3); Magnusson, PKE (3); Zhao, W. (3); Lin, X. (3); Lind, Lars (3); Alameer, E (3); Cheng, CY (3); Psaty, BM (3); Wong, TY (3); Launer, LJ (3); Timpson, NJ (3); Vollenweider, P. (3); Kutalik, Z. (3); Campbell, H (3); Linneberg, A. (3); van Dam, RM (3); Wood, AR (3); Lind, L (3); Wareham, NJ (3); Metspalu, A (3); Gieger, C (3); Frayling, TM (3); Jarvelin, MR (3); Wong, A (3); Hayward, C. (3); Kolcic, I. (3); Spector, TD (3); Vitart, V (3); Wang, YX (3); Chasman, DI (3); Cucca, F (3); Kardia, SLR (3); Ridker, PM (3); Aguilar-Salinas, CA (3); Sabanayagam, C (3); Tai, ES (3); show less...

University: Karolinska Institutet (7); Uppsala University (4); Lund University (3); University of Gothenburg (2); Umeå University (2); University of Skövde (1)

Language: English (7)

Research subject (UKÄ/SCB): Medical and Health Sciences (4)

Year: 2021 (7)Undo refine

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