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Träfflista för sökning "WFRF:(Kallionpaa R.) srt2:(2013-2014)"

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1.	Meinander, K., et al. (author) Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity 2013 In: Medchemcomm. - : Royal Society of Chemistry (RSC). - 2040-2503 .- 2040-2511. ; 4:3, s. 549-553 Journal article (peer-reviewed)abstract Pseudopeptides based on the kallikrein-related peptidase 3 (KLK3) activating bicyclic peptide “C-4” comprising hydrocarbon-based disulphide bridge mimetics have been synthesized. After investigating different synthetic approaches, the pseudopeptides were successfully cyclized from two L-allylglycine side chains via an alkene ring-closing metathesis reaction during the peptide synthesis. The alkene-linker was formed in a 1 : 1 E/Z isomer ratio. The resulting pseudopeptides were almost as potent as the parent peptide, increasing the activity of KLK3 over four-fold at 200 μg ml−1 (130–140 μM) concentrations.
2.	Uusitalo, E, et al. (author) Neurofibromatosis type 1 gene mutation analysis using sequence capture and high-throughput sequencing 2014 In: Acta dermato-venereologica. - : Medical Journals Sweden AB. - 1651-2057 .- 0001-5555. ; 94:6, s. 663-666 Journal article (peer-reviewed)

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Kallionpaa, R. (2); Brandt, A. (1); Poyhonen, M (1); Luthman, Kristina, 1 ... (1); Narvanen, A (1); Peltonen, J. (1); show more...; Stenman, U H (1); Vepsalainen, J. (1); Wallén, Erik A A (1); Jouhilahti, EM (1); Makela, VV (1); Weisell, J (1); Koistinen, H (1); Uusitalo, E. (1); Meinander, K. (1); Pakkala, M. (1); Tadd, A. C. (1); Hekim, C. (1); Widell, K. (1); Soini, J (1); Peltonen, S (1); Hammais, A (1); Palonen, E (1); show less...

University: University of Gothenburg (1); Karolinska Institutet (1)

Language: English (2)

Research subject (UKÄ/SCB): Natural sciences (1)

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