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Träfflista för sökning "WFRF:(Kristal BS) srt2:(1999)"

Search: WFRF:(Kristal BS) > (1999)

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  • Sheu, KFR, et al. (author)
  • A DLST genotype associated with reduced risk for Alzheimer's disease
  • 1999
  • In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 0028-3878 .- 1526-632X. ; 52:7, s. 1505-1507
  • Journal article (peer-reviewed)abstract
    • Article abstract Recent studies suggest that variants of the DLST gene alter the risk of AD. DLST encodes the core subunit of the mitochondrial α-ketoglutarate dehydrogenase complex, which is deficient in AD. The authors report that in 247 US white subjects, homozygosity for DLST A19,117, T19,183 was associated with a reduced risk of AD (odds ratio [OR] = 0.35, p = 0.018). The reduced risk was marked in subjects who did not carry the apolipoprotein (APOE)-4 allele (OR = 0.16, p = 0.014). Further study of DLST in AD appears warranted.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
Kalaria, RN (2)
Lannfelt, L (2)
Lilius, L (2)
Kristal, BS (2)
Sheu, KFR (2)
Brown, AM (2)
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Blass, JP (2)
Haroutunian, V (1)
Thaler, H (1)
Lesser, M (1)
Mohs, RC (1)
Relkin, NR (1)
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University
Karolinska Institutet (2)
Language
English (2)
Year
1999 (2)Undo refine

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