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Träfflista för sökning "WFRF:(Laird A) srt2:(1998-1999)"

Search: WFRF:(Laird A) > (1998-1999)

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1.
  • Dunham, I, et al. (author)
  • The DNA sequence of human chromosome 22
  • 1999
  • In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495
  • Journal article (peer-reviewed)
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2.
  • Weng, Han Rong, et al. (author)
  • GABA(A) receptor blockade inhibits Aβ fibre evoked wind-up in the arthritic rat
  • 1998
  • In: NeuroReport. - : Ovid Technologies (Wolters Kluwer Health). - 0959-4965. ; 9:6, s. 1065-1069
  • Journal article (peer-reviewed)abstract
    • To clarify the mechanisms of allodynia we have examined whether 'wind- up' of nociceptive withdrawal reflexes (NWR), a phenomenon characteristic of nociceptive C fiber spinal processing, can be mimicked by stimulation of tactile Aβ fibers in monoarthritic decerebrate spinal rats. Knee joint monoarthritis was induced by carrageenan/kaolin under halothane anaesthesia 5 h before recordings. In arthritic, but not in control rats, wind-up of NWR of the semitendinosus muscle could be evoked by repeated stimulation of Aβ fibres. By contrast, peroneus longus reflexes did not exhibit marked wind- up. Bicuculline (0.03-0.3 mg/kg, i.v.) dose-dependently inhibited this wind- up. Hence, reflex wind-up can be elicited by tactile Aβ fibers in arthritic rats through a GABA(A) dependent mechanism.
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