↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Laterre PF) "

Search: WFRF:(Laterre PF)

Result 1-3 of 3

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Bellomo, R, et al. (author) Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference 2017 In: Annals of intensive care. - : Springer Science and Business Media LLC. - 2110-5820. ; 7:1, s. 49- Journal article (peer-reviewed)
2.	Sartelli, M, et al. (author) Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) 2016 In: World journal of emergency surgery : WJES. - : Springer Science and Business Media LLC. - 1749-7922. ; 11, s. 33- Journal article (peer-reviewed)
3.	Van Daele, R, et al. (author) A Large Retrospective Assessment of Voriconazole Exposure in Patients Treated with Extracorporeal Membrane Oxygenation 2021 In: Microorganisms. - : MDPI AG. - 2076-2607. ; 9:7 Journal article (peer-reviewed)abstract Background: Voriconazole is one of the first-line therapies for invasive pulmonary aspergillosis. Drug concentrations might be significantly influenced by the use of extracorporeal membrane oxygenation (ECMO). We aimed to assess the effect of ECMO on voriconazole exposure in a large patient population. Methods: Critically ill patients from eight centers in four countries treated with voriconazole during ECMO support were included in this retrospective study. Voriconazole concentrations were collected in a period on ECMO and before/after ECMO treatment. Multivariate analyses were performed to evaluate the effect of ECMO on voriconazole exposure and to assess the impact of possible saturation of the circuit’s binding sites over time. Results: Sixty-nine patients and 337 samples (190 during and 147 before/after ECMO) were analyzed. Subtherapeutic concentrations (<2 mg/L) were observed in 56% of the samples during ECMO and 39% without ECMO (p = 0.80). The median trough concentration, for a similar daily dose, was 2.4 (1.2–4.7) mg/L under ECMO and 2.5 (1.4–3.9) mg/L without ECMO (p = 0.58). Extensive inter-and intrasubject variability were observed. Neither ECMO nor squared day of ECMO (saturation) were retained as significant covariates on voriconazole exposure. Conclusions: No significant ECMO-effect was observed on voriconazole exposure. A large proportion of patients had voriconazole subtherapeutic concentrations.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-3 of 3

Refine your search

Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Zhang, L. (1); Kumar, A. (1); Taccone, FS (1); Hansen, S. (1); Negoi, I (1); Abu-Zidan, FM (1); show more...; Coccolini, F (1); Ansaloni, L (1); Di Saverio, S (1); Griffiths, EA (1); Isik, A (1); Soreide, K (1); Sganga, G (1); Catena, F (1); Agresta, F (1); Jusoh, AC (1); Karamarkovic, A (1); Bhangu, A (1); Nord, CE (1); Gkiokas, G (1); Piazza, D. (1); Martensson, J (1); Leone, M (1); Ronco, C (1); Haque, M. (1); Patel, B (1); Reed, A. (1); Viscoli, C (1); Bellomo, R (1); Broman, LM (1); Ruppé, E. (1); Vincent, JL (1); Duranteau, J (1); Rocha, C (1); Legrand, M. (1); Bassetti, M (1); Malbrain, MLNG (1); Giamarellou, H. (1); Darmon, M. (1); Eckmann, C (1); Chandy, SJ (1); Li, YS (1); Lindfors, M (1); van Goor, H (1); Koike, K (1); De Waele, JJ (1); Martin-Loeches, I (1); Timsit, JF (1); Wauters, J (1); Hecker, A. (1); show less...

University: Karolinska Institutet (3)

Language: English (3)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view