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- Eriksson, Barbro, et al.
(author)
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Neuroendocrine pancreatic tumours : clinical presentation, biochemical and histopathological findings in 84 patients
- 1990
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In: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 228:2, s. 103-113
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Journal article (peer-reviewed)abstract
- A prospective study has been performed on 84 patients with endocrine pancreatic tumours evaluated at the Medical Department in Uppsala. Available information concerning the patients' presenting symptoms, age at diagnosis, clinical syndrome, tumour location, location of metastases, diagnostic radiology, biochemical and histopathological findings has been analysed. Our results indicate that most patients initially show rather vague and non-specific symptoms, with dyspepsia and pain being the most frequent presenting features. The median delay between appearance of the first symptom and diagnosis was 2 years; the delay was 3 5 months in sporadic cases and 14.5 months in familial cases. In spite of improvements in diagnostic methods, the median age at diagnosis (53 years) has not been reduced, and most patients are encountered when the tumour has reached an advanced stage. There is a need for a method of screening patients with still uncharacteristic abdominalsymptoms for a neuroendocrine tumour. The presence of elevated levels of plasma chromogranin in all patients with a proven tumour suggests that such possibilities exist, and the use of this biochemical marker in the future might reduce the age at diagnosis and thus improve the likelihood of cure and survival of patients with endocrine pancreatic tumours.
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- Holst, LE, et al.
(author)
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Investigation of peat pyrolysis under inert gas atmosphere
- 1991
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In: Fuel. - : Elsevier BV. - 1873-7153 .- 0016-2361. ; 70:9, s. 1017-1022
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Journal article (peer-reviewed)abstract
- Seven Swedish peats of different degrees of humification were pyrolysed in a thermobalance at pressures in the range 1.0-4.0 MPa. The formation kinetics of the pyrolysis products were determined using the non-isothermal evaluation method. The sample size used was 1.0 g and the heating rate was 10 K min-1. Gas production was analysed by gas chromatography and the components were CO2, C2H4, C2H6, CH4 and CO. The tar and char production were measured after the experiment by weighing. The experiments showed that gas production was slightly increased, at the expense of tar production, with increasing pressure, indicating some thermal cracking. The kinetic parameters, i.e. pre-exponential factor, k0, and activation energy, E(a), were unaffected by the pressure.
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